Nifedipine and Glynase drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nifedipine (nifedipine) and Glynase (glyburide). Common drug interactions include asthma among females and alanine aminotransferase increased among males.
The phase IV clinical study analyzes what interactions people have when they take Nifedipine and Glynase. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Nifedipine?
Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.
What is Glynase?
Glynase has active ingredients of glyburide. eHealthMe is studying from 1,513 Glynase users. Check the latest studies of Glynase.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
41 people who take Nifedipine and Glynase together, and have interactions are studied.

What are the common drug interactions of Nifedipine and Glynase, by gender? *:
female:
- Asthma
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cardiomegaly (increased size of heart than normal)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Cerebrovascular disorder (disease of brain)
- Chest pain
- Chronic obstructive airways disease
- Confusion
male:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Hepatic function abnormal
- Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
- Pleural effusion (water on the lungs)
- Atrioventricular block complete (heart block complete)
- Blood urea increased
- Dementia (madness)
- Electrocardiogram st segment elevation
- Renal failure (kidney dysfunction)
What are the common drug interactions of Nifedipine and Glynase, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Asthenia (weakness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Cardiac disorder
- Cardiac failure chronic
- Cardiac valve disease (heart valve disease)
50-59:
- Blood creatinine increased
- Blood glucose increased
- Bradycardia (abnormally slow heart action)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fatigue (feeling of tiredness)
- Oedema (fluid collection in tissue)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Pancreatic cyst
- Pancreatitis acute (sudden inflammation of pancreas)
- Weight decreased
60+:
- Renal failure (kidney dysfunction)
- Cardiac failure
- Gamma-glutamyltransferase increased
- Hyperkalaemia (damage to or disease of the kidney)
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
- Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
- Vitreous haemorrhage (intraocular (inside the eye) bleeding)
- Asthenia (weakness)
- Dehydration (dryness resulting from the removal of water)
- Diabetic retinopathy (damage to the retina caused by complications of diabetes)
What are the existing conditions these people have? *
- Arrhythmias (irregular heartbeat): 6 people, 14.63%
* Approximation only. Some reports may have incomplete information.
Do you take Nifedipine and Glynase?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Nifedipine (53,459 reports)
- Glynase (1,513 reports)
Browse all drug interactions of Nifedipine and Glynase:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nifedipine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Glynase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nifedipine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glynase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nifedipine and glyburide (the active ingredients of Nifedipine and Glynase, respectively), and Nifedipine and Glynase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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