Nifedipine and Nitro-bid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nifedipine (nifedipine) and Nitro-bid (nitroglycerin). Common drug interactions include blood pressure fluctuation among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Nifedipine and Nitro-bid. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Nitro-bid?

Nitro-bid has active ingredients of nitroglycerin. eHealthMe is studying from 653 Nitro-bid users. Check the latest studies of Nitro-bid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

20 people who take Nifedipine and Nitro-bid together, and have interactions are studied.

Nifedipine and Nitro-bid drug interactions.

What are the common drug interactions of Nifedipine and Nitro-Bid, by gender? *:

female:

Blood pressure fluctuation
Cardiac failure
Dry eye (lack of adequate tears)
Epistaxis (bleed from the nose)
Eye irritation
Eye pain
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Joint swelling
Ocular hyperaemia (an abnormally large amount of blood in eye)

male:

Depression
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers)
Muscle contracture (a permanent shortening of a muscle)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Onychomadesis (a periodic idiopathic shedding of the nails)
Pain
Rash

What are the common drug interactions of Nifedipine and Nitro-Bid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain
Subclavian artery stenosis (the abnormal narrowing of subclavian artery)
Subclavian artery thrombosis (a condition in which the blood flow through the vessel is obstructed)
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)

40-49:

Autonomic dysreflexia (state that is unique to patients after spinal cord injury at a t-5 level and above)
Bladder spasm
Constipation
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

Epistaxis (bleed from the nose)
Headache (pain in head)
Joint swelling
Disease progression
Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Scleroderma (hard skin)
Vomiting

60+:

Skin exfoliation (removal of the oldest dead skin cells)
Depression
Mobility decreased (ability to move is reduced)
Muscle contracture (a permanent shortening of a muscle)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Onychomadesis (a periodic idiopathic shedding of the nails)
Pain

What are the existing conditions these people have? *

Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 4 people, 20.00%
Rash Pruritic (redness with itching): 3 people, 15.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 15.00%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 2 people, 10.00%
Birth Control: 2 people, 10.00%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 10.00%
Ulcerative Keratitis (ulcerative inflammation of the cornea): 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%
Asthma: 1 person, 5.00%
Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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