Nifedipine and Roxicodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nifedipine (nifedipine) and Roxicodone (oxycodone hydrochloride). Common drug interactions include headache among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Nifedipine and Roxicodone. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.



On Jul, 16, 2026

21 people who take Nifedipine and Roxicodone together, and have interactions are studied.

Nifedipine and Roxicodone drug interactions.

What are the common drug interactions of Nifedipine and Roxicodone, by gender? *:

female:

  1. Headache (pain in head)
  2. Hepatic enzyme increased
  3. Hepatitis c
  4. Hot flush (sudden feelings of heat)
  5. Hunger
  6. Muscle spasms (muscle contraction)
  7. Myositis (inflammation of the muscles)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Oropharyngeal pain
  10. Pancreatitis acute (sudden inflammation of pancreas)

male:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Abdominal discomfort
  3. Erythema (redness of the skin)
  4. Essential hypertension (primary hypertension)
  5. Genital lesion (sores, warts, or blemishes that appear on the genitals)
  6. Gout (uric acid crystals building up in the body)
  7. Haematocrit decreased
  8. Haemoglobin decreased
  9. Herpes simplex (herpes simplex is a common viral infection)
  10. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

What are the common drug interactions of Nifedipine and Roxicodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cough
  2. Dysphonia (speech disorder attributable to a disorder of phonation)
  3. Headache (pain in head)
  4. Hot flush (sudden feelings of heat)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Oropharyngeal pain

50-59:

  1. Pneumonia
  2. Renal failure (kidney dysfunction)
  3. Stress
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Muscular weakness (muscle weakness)
  8. Nausea (feeling of having an urge to vomit)
  9. Nervousness
  10. Night sweats (sweating in night)

60+:

  1. Pyrexia (fever)
  2. Abdominal discomfort
  3. Erythema (redness of the skin)
  4. Essential hypertension (primary hypertension)
  5. Gout (uric acid crystals building up in the body)
  6. Haematocrit decreased
  7. Haemoglobin decreased
  8. Herpes simplex (herpes simplex is a common viral infection)
  9. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  10. Hypercholesterolaemia (high levels of cholesterol in the blood)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 6 people, 28.57%
  2. Wheezing (a high-pitched whistling sound made while you breath): 5 people, 23.81%
  3. Essential Hypertension (primary hypertension): 5 people, 23.81%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 23.81%
  5. Nausea And Vomiting: 5 people, 23.81%
  6. Muscle Spasms (muscle contraction): 4 people, 19.05%
  7. Depression: 4 people, 19.05%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 19.05%
  9. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 4 people, 19.05%
  10. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nifedipine and Roxicodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Roxicodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nifedipine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Roxicodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine and oxycodone hydrochloride (the active ingredients of Nifedipine and Roxicodone, respectively), and Nifedipine and Roxicodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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