Nipent and Prednisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nipent (pentostatin) and Prednisone (prednisone). Common drug interactions include body temperature increased among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Nipent and Prednisone. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Nipent?

Nipent has active ingredients of pentostatin. eHealthMe is studying from 301 Nipent users. Check the latest studies of Nipent.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

12 people who take Nipent and Prednisone together, and have interactions are studied.

Nipent and Prednisone drug interactions.

What are the common drug interactions of Nipent and Prednisone, by gender? *:

female:

  1. Body temperature increased
  2. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  3. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Blood creatine increased
  6. Blood glucose increased
  7. Blood potassium increased
  8. Blood pressure systolic increased
  9. Blood urea increased
  10. Blood urine present

male:

  1. Cough
  2. Confusional state
  3. Acute respiratory distress syndrome
  4. Agitation (state of anxiety or nervous excitement)
  5. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  6. Asthenia (weakness)
  7. Blood culture positive
  8. Blood pressure systolic decreased
  9. Body temperature increased
  10. Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Nipent and Prednisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  2. Bone marrow failure
  3. Cough
  4. Diarrhoea
  5. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  6. Pneumonia escherichia (pneumonia due to bacteria escherichia coli)
  7. Pyrexia (fever)
  8. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

20-29:

  1. Abdominal pain
  2. Epstein-barr virus infection
  3. Lymphoma (cancer that begins in immune system cells)
  4. Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
  5. Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

  1. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  2. Body temperature increased
  3. Cough
  4. Diarrhoea
  5. Fatigue (feeling of tiredness)
  6. Gastroenteritis (inflammation of stomach and intestine)
  7. Leukocytosis (increased white blood cells)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Muscle cramp (painful sensation caused by muscle contraction)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Blood creatine increased
  4. Blood glucose increased
  5. Blood potassium increased
  6. Blood pressure systolic increased
  7. Blood urea increased
  8. Blood urine present
  9. Body temperature increased
  10. Coma (state of unconsciousness lasting more than six hours)

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Acute respiratory distress syndrome
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Cough
  5. Dehydration (dryness resulting from the removal of water)
  6. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  7. Diarrhoea
  8. Disease progression
  9. Dyspnoea (difficult or laboured respiration)
  10. Faecal incontinence (a lack of control over passing stool)

What are the existing conditions these people have? *

  1. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 50.00%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 16.67%
  3. Hairy Cell Leukaemia (a type of blood cancer): 1 person, 8.33%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nipent and Prednisone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nipent and Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nipent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nipent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pentostatin and prednisone (the active ingredients of Nipent and Prednisone, respectively), and Nipent and Prednisone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: