Nitro-bid and Zestril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nitro-bid (nitroglycerin) and Zestril (lisinopril). Common drug interactions include eosinophil count increased among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Nitro-bid and Zestril. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Nitro-bid?
Nitro-bid has active ingredients of nitroglycerin. eHealthMe is studying from 653 Nitro-bid users. Check the latest studies of Nitro-bid.
What is Zestril?
Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
17 people who take Nitro-bid and Zestril together, and have interactions are studied.

What are the common drug interactions of Nitro-Bid and Zestril, by gender? *:
female:
- Eosinophil count increased
- Epistaxis (bleed from the nose)
- Faeces discoloured
- Gastric ulcer (stomach ulcer)
- General physical health deterioration (weak health status)
- Haematocrit decreased
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
- Hip fracture
- Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
male:
- Pain
- Depression
- Mobility decreased (ability to move is reduced)
- Muscle contracture (a permanent shortening of a muscle)
- Muscular weakness (muscle weakness)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Oedema peripheral (superficial swelling)
- Onychomadesis (a periodic idiopathic shedding of the nails)
- Rash
What are the common drug interactions of Nitro-Bid and Zestril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
50-59:
- Acute myocardial infarction (acute heart attack)
- Confusional state
- Depressed level of consciousness
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Epistaxis (bleed from the nose)
- Faeces discoloured
- Fall
- General physical health deterioration (weak health status)
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
60+:
- Depression
- Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers)
- Muscle contracture (a permanent shortening of a muscle)
- Muscular weakness (muscle weakness)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Oedema peripheral (superficial swelling)
- Onychomadesis (a periodic idiopathic shedding of the nails)
- Pain
- Rash
What are the existing conditions these people have? *
- Rash Pruritic (redness with itching): 3 people, 17.65%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
- Stress And Anxiety: 1 person, 5.88%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
- Rashes (redness): 1 person, 5.88%
- Pain: 1 person, 5.88%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.88%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Nitro-bid and Zestril?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nitro-bid and Zestril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nitro-bid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zestril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitro-bid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zestril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on nitroglycerin and lisinopril (the active ingredients of Nitro-bid and Zestril, respectively), and Nitro-bid and Zestril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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