Nitro-dur and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitro-dur (nitroglycerin) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include pyrexia among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Nitro-dur and Bactrim. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Nitro-dur?

Nitro-dur has active ingredients of nitroglycerin. eHealthMe is studying from 2,414 Nitro-dur users. Check the latest studies of Nitro-dur.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

19 people who take Nitro-dur and Bactrim together, and have interactions are studied.

Nitro-dur and Bactrim drug interactions.

What are the common drug interactions of Nitro-Dur and Bactrim, by gender? *:

female:

Pyrexia (fever)
Toothache (tooth pain)
Vomiting
Weight decreased
Chest pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Asthenia (weakness)
Cardiac failure congestive
Renal failure acute (rapid kidney dysfunction)
Colitis (inflammation of colon)

male:

Cardiac disorder
Abdominal distension
Calcinosis (calcium deposits in any soft tissue)
Cardiac failure
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic kidney disease
Coma (state of unconsciousness lasting more than six hours)

What are the common drug interactions of Nitro-Dur and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Abdominal pain
Anxiety
Bulimia nervosa (eating disorder characterized by recurrent binge eating, followed by compensatory behaviours)
Calcinosis (calcium deposits in any soft tissue)
Cardiac disorder
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Chest pain
Colitis (inflammation of colon)

40-49:

n/a

50-59:

Chronic kidney disease
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Renal failure (kidney dysfunction)

60+:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Chest pain
Blood glucose decreased
Bradycardia (abnormally slow heart action)
Cardiac failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coma (state of unconsciousness lasting more than six hours)
Confusion
Death
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 21.05%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
Stable Angina (a constant chest pain): 1 person, 5.26%
Pain: 1 person, 5.26%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 5.26%
High Blood Pressure: 1 person, 5.26%
Heart Disease: 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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