Nitrofurantoin and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrofurantoin (nitrofurantoin, macrocrystalline) and Evista (raloxifene hydrochloride). Common drug interactions include anxiety among females and scar among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrofurantoin and Evista. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.



On Jul, 26, 2026

48 people who take Nitrofurantoin and Evista together, and have interactions are studied.

Nitrofurantoin and Evista drug interactions.

What are the common drug interactions of Nitrofurantoin and Evista, by gender? *:

female:

  1. Anxiety
  2. Dyspnoea (difficult or laboured respiration)
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Back pain
  5. Fall
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Diarrhoea
  9. Myalgia (muscle pain)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Scar
  2. Acute sinusitis
  3. Bone loss
  4. Candidiasis (candidiasis or thrush is a fungal infection)
  5. Cellulitis (infection under the skin)
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  8. Constipation
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Decreased appetite

What are the common drug interactions of Nitrofurantoin and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Scar
  2. Acute sinusitis
  3. Anaemia (lack of blood)
  4. Angiopathy (generic term for a disease of the blood vessels)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Aortic arteriosclerosis (hardening of the aortic arteries)
  8. Arthropathy
  9. Back pain
  10. Bone disorder

10-19:

  1. Abdominal distension
  2. Acquired oesophageal web (structural abnormalities in the oesophagus)
  3. Anaemia (lack of blood)
  4. Anxiety
  5. Apnoea (suspension of external breathing)
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Back pain
  10. Bedridden

20-29:

n/a

30-39:

n/a

40-49:

  1. Bacterial infection
  2. Cellulitis (infection under the skin)
  3. Excoriation (to tear or wear off the skin of)
  4. Fall
  5. Feeling hot
  6. Influenza like illness
  7. Injection site reaction
  8. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Sweating increased (excess sweating)
  10. Wound infection

50-59:

  1. Injury
  2. Atelectasis (partial or complete collapse of the lung)
  3. Dyspnoea (difficult or laboured respiration)
  4. Ovarian cancer metastatic (cancer of ovary spreads to other organ or parts)
  5. Pleural effusion (water on the lungs)
  6. Surgery
  7. Tooth extraction
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Toothache (tooth pain)
  10. Acquired oesophageal web (structural abnormalities in the oesophagus)

60+:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Back pain
  3. Anxiety
  4. Aortic arteriosclerosis (hardening of the aortic arteries)
  5. Bone disorder
  6. Cellulitis (infection under the skin)
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Decreased appetite

What are the existing conditions these people have? *

  1. Herpes Virus Infection: 16 people, 33.33%
  2. Ovarian Cancer (cancer of ovary): 10 people, 20.83%
  3. Nausea (feeling of having an urge to vomit): 10 people, 20.83%
  4. Muscle Aches (muscle pain): 10 people, 20.83%
  5. Insomnia (sleeplessness): 10 people, 20.83%
  6. Breast Cancer: 9 people, 18.75%
  7. Depression: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrofurantoin and Evista?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitrofurantoin and Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrofurantoin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evista and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline and raloxifene hydrochloride (the active ingredients of Nitrofurantoin and Evista, respectively), and Nitrofurantoin and Evista (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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