Nitrofurantoin and Indapamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrofurantoin (nitrofurantoin, macrocrystalline) and Indapamide (indapamide). Common drug interactions include cardiac arrest among females.

The phase IV clinical study analyzes what interactions people have when they take Nitrofurantoin and Indapamide. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

What is Indapamide?

Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,152 Indapamide users. Check the latest studies of Indapamide.



On Jul, 06, 2026

12 people who take Nitrofurantoin and Indapamide together, and have interactions are studied.

Nitrofurantoin and Indapamide drug interactions.

What are the common drug interactions of Nitrofurantoin and Indapamide, by gender? *:

female:

  1. Cardiac arrest
  2. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  3. Depression
  4. Dizziness
  5. Headache (pain in head)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Mitral valve incompetence (inefficient heart valve)
  8. Nausea (feeling of having an urge to vomit)
  9. Road traffic accident
  10. Abdominal distension

male:

n/a

What are the common drug interactions of Nitrofurantoin and Indapamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Asthenia (weakness)
  2. Chest pain
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Dyspnoea (difficult or laboured respiration)
  5. Headache (pain in head)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Mitral valve incompetence (inefficient heart valve)
  8. Neuropathy peripheral (surface nerve damage)
  9. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)

50-59:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Chorea (abnormal involuntary movement disorder)
  4. Constipation
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Decreased activity
  7. Depression
  8. Diabetic vascular disorder (diseases of the blood vessels due to diabetes)
  9. Dizziness
  10. Dysaesthesia (abnormal sensation)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 3 people, 25.00%
  2. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 2 people, 16.67%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
  5. Arrhythmias (irregular heartbeat): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrofurantoin and Indapamide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitrofurantoin and Indapamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Indapamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrofurantoin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Indapamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitrofurantoin, macrocrystalline and indapamide (the active ingredients of Nitrofurantoin and Indapamide, respectively), and Nitrofurantoin and Indapamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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