Nitroglycerin and Firdapse drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitroglycerin (nitroglycerin) and Firdapse (amifampridine). Common drug interactions include drug ineffective among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Nitroglycerin and Firdapse. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Nitroglycerin?

Nitroglycerin has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 52,884 Nitroglycerin users. Check the latest studies of Nitroglycerin.

What is Firdapse?

Firdapse has active ingredients of amifampridine. eHealthMe is studying from 2,112 Firdapse users. Check the latest studies of Firdapse.



On Jul, 15, 2026

13 people who take Nitroglycerin and Firdapse together, and have interactions are studied.

Nitroglycerin and Firdapse drug interactions.

What are the common drug interactions of Nitroglycerin and Firdapse, by gender? *:

female:

  1. Drug ineffective
  2. Tremor (trembling or shaking movements in one or more parts of your body)
  3. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  4. Small cell lung cancer (small cell cancer tumour of lung)
  5. Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)

male:

  1. Weight decreased
  2. Dyspnoea (difficult or laboured respiration)
  3. Feeling drunk
  4. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  5. Hypertension (high blood pressure)
  6. Knee arthroplasty
  7. Muscular weakness (muscle weakness)
  8. Pneumonia
  9. Burns second degree
  10. Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Nitroglycerin and Firdapse, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Burns second degree
  2. Drug ineffective
  3. Dyspnoea (difficult or laboured respiration)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  6. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  7. Nerve injury
  8. Neuromyopathy (disease of both muscles and nerves)
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)

60+:

  1. Drug ineffective
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Glossodynia (a burning or painful sensation in the tongue)
  4. Hypercapnia (too much smoke)
  5. Neck pain
  6. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  7. Respiration (transport of oxygen from the outside air to the cells within tissues)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Change of bowel habit
  10. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

What are the existing conditions these people have? *

  1. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 13 people, 100.00%
  2. Pain: 1 person, 7.69%
  3. Nausea (feeling of having an urge to vomit): 1 person, 7.69%
  4. Lung Cancer - Small Cell (lung cancer): 1 person, 7.69%
  5. Asthma: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Nitroglycerin and Firdapse?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitroglycerin and Firdapse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitroglycerin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Firdapse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitroglycerin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Firdapse and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin and amifampridine (the active ingredients of Nitroglycerin and Firdapse, respectively), and Nitroglycerin and Firdapse (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: