Nitrol and Alprazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrol (nitroglycerin) and Alprazolam (alprazolam). Common drug interactions include cardiac failure congestive among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrol and Alprazolam. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrol?

Nitrol has active ingredients of nitroglycerin. eHealthMe is studying from 3,069 Nitrol users. Check the latest studies of Nitrol.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.



On Jul, 19, 2026

50 people who take Nitrol and Alprazolam together, and have interactions are studied.

Nitrol and Alprazolam drug interactions.

What are the common drug interactions of Nitrol and Alprazolam, by gender? *:

female:

  1. Cardiac failure congestive
  2. Chest pain
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  5. Constipation
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Cystitis interstitial (unknown cause characterized by bladder pain)
  9. Death
  10. Decreased appetite

male:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Vomiting
  4. Weight decreased
  5. Back pain
  6. Confusional state
  7. Death
  8. Depression
  9. Emotional distress
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Nitrol and Alprazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Arrhythmia (irregular heartbeat)
  3. Back pain
  4. Chest pain
  5. Epistaxis (bleed from the nose)
  6. Rash
  7. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

  1. Renal injury (kidney injury)
  2. Pancreatitis acute (sudden inflammation of pancreas)
  3. Chronic kidney disease
  4. Renal failure (kidney dysfunction)
  5. Renal impairment (severely reduced kidney function)

50-59:

  1. Hospitalisation
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Diarrhoea
  4. Nephrolithiasis (calculi in the kidneys)
  5. Coronary arterial stent insertion
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Impaired gastric emptying
  8. Nerve compression

60+:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Asthenia (weakness)
  3. Diarrhoea
  4. Dizziness
  5. Hypertensive heart disease
  6. Hypokalaemia (low potassium)
  7. International normalised ratio increased
  8. Loss of consciousness
  9. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  10. Muscle fatigue (a condition in which muscles cannot exert their normal force)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 8 people, 16.00%
  2. Pain: 5 people, 10.00%
  3. High Blood Pressure: 4 people, 8.00%
  4. Depression: 4 people, 8.00%
  5. Type 2 Diabetes: 3 people, 6.00%
  6. Panic Disorder: 3 people, 6.00%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.00%
  8. Mood Swings (an extreme or rapid change in mood): 3 people, 6.00%
  9. Enlarged Prostate: 3 people, 6.00%
  10. Constipation: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrol and Alprazolam?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitrol and Alprazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alprazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alprazolam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin and alprazolam (the active ingredients of Nitrol and Alprazolam, respectively), and Nitrol and Alprazolam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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