Nitrol and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrol (nitroglycerin) and Avapro (irbesartan). Common drug interactions include myocardial infarction among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrol and Avapro. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrol?

Nitrol has active ingredients of nitroglycerin. eHealthMe is studying from 3,069 Nitrol users. Check the latest studies of Nitrol.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

17 people who take Nitrol and Avapro together, and have interactions are studied.

What are the common drug interactions of Nitrol and Avapro, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal failure chronic (long lasting kidney dysfunction)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Haemoglobin decreased
Iron deficiency anaemia
Cerebral haemorrhage (bleeding within the brain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Blood potassium increased
Confusional state

male:

Acute myocardial infarction (acute heart attack)
Aortic aneurysm rupture (enlarged aortic artery rapture caused by a weakening of the artery wall)
Death
Glaucoma (increased fluid pressure in the eye with vision loss)
Pharyngoesophageal diverticulum
Prostatic specific antigen increased

What are the common drug interactions of Nitrol and Avapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cardiac failure
Cerebral haemorrhage (bleeding within the brain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Blood potassium increased
Confusional state
Abdominal infection
Acute myocardial infarction (acute heart attack)
Cardiac failure congestive
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the existing conditions these people have? *

Stable Angina (a constant chest pain): 6 people, 35.29%
Cardiac Disorder: 5 people, 29.41%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 29.41%
High Density Lipoprotein Increased: 4 people, 23.53%
Blood Potassium Decreased: 4 people, 23.53%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 23.53%
Cardiac Failure Congestive: 4 people, 23.53%
Sleep Disorder: 4 people, 23.53%
Joint Pain: 3 people, 17.65%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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