Nitrol and Nuvigil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrol (nitroglycerin) and Nuvigil (armodafinil). Common drug interactions include eczema among females and arthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrol and Nuvigil. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrol?

Nitrol has active ingredients of nitroglycerin. eHealthMe is studying from 3,069 Nitrol users. Check the latest studies of Nitrol.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

21 people who take Nitrol and Nuvigil together, and have interactions are studied.

Nitrol and Nuvigil drug interactions.

What are the common drug interactions of Nitrol and Nuvigil, by gender? *:

female:

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  2. Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
  3. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  4. Pulmonary hypertension (increase in blood pressure in the lung artery)
  5. Blood pressure increased
  6. Hospitalisation
  7. Osteoporosis (bones weak and more likely to break)
  8. Pain
  9. Deafness
  10. Depression

male:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Blood pressure increased
  3. Type 2 diabetes mellitus
  4. Cataract (clouding of the lens inside the eye)
  5. Oxygen saturation decreased
  6. Pancreatitis (inflammation of pancreas)
  7. Suicidal ideation
  8. Oedema peripheral (superficial swelling)
  9. Pulmonary oedema (fluid accumulation in the lungs)
  10. Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the common drug interactions of Nitrol and Nuvigil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Post procedural haemorrhage (post procedural bleeding)
  2. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  3. Psoriasis (immune-mediated disease that affects the skin)
  4. Suicidal ideation
  5. Type 2 diabetes mellitus
  6. Sinusitis (inflammation of sinus)
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Blood pressure increased
  10. Cataract (clouding of the lens inside the eye)

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 57.14%
  2. Drowsiness: 3 people, 14.29%
  3. Apnea (temporary absence or cessation of breathing): 3 people, 14.29%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 9.52%
  5. Hypersensitivity: 2 people, 9.52%
  6. High Blood Pressure: 2 people, 9.52%
  7. High Blood Cholesterol: 2 people, 9.52%
  8. Eye Disorder: 2 people, 9.52%
  9. Constipation: 2 people, 9.52%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrol and Nuvigil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitrol and Nuvigil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nuvigil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuvigil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin and armodafinil (the active ingredients of Nitrol and Nuvigil, respectively), and Nitrol and Nuvigil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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