Nitrolingual and Ibu drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nitrolingual (nitroglycerin) and Ibu (ibuprofen). Common drug interactions include anxiety among females and general physical health deterioration among males.
The phase IV clinical study analyzes what interactions people have when they take Nitrolingual and Ibu. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.
What is Nitrolingual?
Nitrolingual has active ingredients of nitroglycerin. eHealthMe is studying from 2,777 Nitrolingual users. Check the latest studies of Nitrolingual.
What is Ibu?
Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.
100 people who take Nitrolingual and Ibu together, and have interactions are studied.

What are the common drug interactions of Nitrolingual and Ibu, by gender? *:
female:
- Anxiety
- Cardiac failure
- Hypotension (abnormally low blood pressure)
- Muscle spasms (muscle contraction)
- Oropharyngeal pain
- Pneumonia
- Renal failure (kidney dysfunction)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Sinusitis (inflammation of sinus)
- Abdominal distension
male:
- General physical health deterioration (weak health status)
- Localised infection (infection at the single location)
- Malignant melanoma stage i (cancer has formed; the tumour is not more than 1 millimetre thick, with no ulceration)
- Asthenia (weakness)
- Cold sweat
- Malignant melanoma (skin cancer rises from melancytes)
- Chest pain
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Death
- Depression
What are the common drug interactions of Nitrolingual and Ibu, by age (0-1 to 60+)? *:
0-1:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Coronary artery stenosis (narrowing of coronary artery)
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Fear
- Injury
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Renal injury (kidney injury)
- Stress
50-59:
- Dyspnoea (difficult or laboured respiration)
- Malaise (a feeling of general discomfort or uneasiness)
- Memory impairment
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pain in extremity
- Suicidal ideation
- Vomiting
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Chest pain
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
60+:
- Hypertension (high blood pressure)
- Chronic kidney disease
- Nausea (feeling of having an urge to vomit)
- Malignant melanoma (skin cancer rises from melancytes)
- Mobility decreased (ability to move is reduced)
- Pain in extremity
- Alopecia (absence of hair from areas of the body)
- Renal failure (kidney dysfunction)
- Cardiac arrest
- Cardiac failure
What are the existing conditions these people have? *
- High Blood Pressure: 21 people, 21.00%
- Immunodeficiency Common Variable: 6 people, 6.00%
- High Blood Cholesterol: 6 people, 6.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.00%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Nitrolingual and Ibu?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Nitrolingual (2,777 reports)
- Ibu (246,531 reports)
Browse all drug interactions of Nitrolingual and Ibu:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nitrolingual:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibu:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitrolingual and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibu and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on nitroglycerin and ibuprofen (the active ingredients of Nitrolingual and Ibu, respectively), and Nitrolingual and Ibu (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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