Nitrostat and Keytruda drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nitrostat (nitroglycerin) and Keytruda (pembrolizumab). Common drug interactions include decreased appetite among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Nitrostat and Keytruda. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Nitrostat?
Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.
What is Keytruda?
Keytruda has active ingredients of pembrolizumab. It is often used in renal cell carcinoma. eHealthMe is studying from 57,404 Keytruda users. Check the latest studies of Keytruda.
15 people who take Nitrostat and Keytruda together, and have interactions are studied.

What are the common drug interactions of Nitrostat and Keytruda, by gender? *:
female:
- Decreased appetite
- Abdominal pain upper
- Back pain
- Blood pressure increased
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dysuria (painful or difficult urination)
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
- Hypophagia (reduced food intake)
male:
- Asthenia (weakness)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Metastases to abdominal cavity (cancer spreads to abdominal cavity)
- Metastases to lung (cancer spreads to lung)
- Metastases to pelvis (cancer spreads to pelvis)
- Metastases to thorax (cancer spreads to thorax)
- Blood bilirubin increased
- Blood sodium decreased
- Cellulitis (infection under the skin)
- Death
What are the common drug interactions of Nitrostat and Keytruda, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Decreased appetite
- Malignant neoplasm progression (cancer tumour came back)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dysuria (painful or difficult urination)
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
- Hypertension (high blood pressure)
- Hypophagia (reduced food intake)
- Muscle spasms (muscle contraction)
What are the existing conditions these people have? *
- Endometrial Cancer: 4 people, 26.67%
- Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 2 people, 13.33%
- Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 6.67%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 6.67%
- Depression: 1 person, 6.67%
- Enlarged Prostate: 1 person, 6.67%
- Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 6.67%
- High Blood Cholesterol: 1 person, 6.67%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%
- Joint Pain: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Nitrostat and Keytruda?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nitrostat and Keytruda:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nitrostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Keytruda:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitrostat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keytruda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nitroglycerin and pembrolizumab (the active ingredients of Nitrostat and Keytruda, respectively), and Nitrostat and Keytruda (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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