Nitrostat and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrostat (nitroglycerin) and Rapamune (sirolimus). Common drug interactions include immunosuppressant drug level increased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrostat and Rapamune. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

23 people who take Nitrostat and Rapamune together, and have interactions are studied.

Nitrostat and Rapamune drug interactions.

What are the common drug interactions of Nitrostat and Rapamune, by gender? *:

female:

Immunosuppressant drug level increased
Abdominal discomfort
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Bone loss
Hearing impaired
Renal hypertrophy (over growth of kidney)
Blood potassium decreased
Eye haemorrhage (bleeding in the eye)
Fall
Hyperlipidaemia (presence of excess lipids in the blood)

male:

Pneumonia
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Blood creatine phosphokinase mb increased
Blood glucose fluctuation
Blood phosphorus decreased
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)

What are the common drug interactions of Nitrostat and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Abdominal discomfort
Influenza
Eye haemorrhage (bleeding in the eye)
Vision blurred
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

50-59:

Aphthous stomatitis (mouth ulcer)
Arteriosclerosis (thickening and hardening of arteries)
Asthma
Back pain
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Blood glucose fluctuation
Blood phosphorus decreased
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Pneumonia
Blood cholesterol increased
Herpes zoster
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pulmonary oedema (fluid accumulation in the lungs)
Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
Blood potassium decreased
Fall
Loss of consciousness
Swelling

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 17.39%
Bone Disorder: 4 people, 17.39%
Blood Pressure Abnormal: 4 people, 17.39%
Blood Glucose Abnormal: 4 people, 17.39%
Abdominal Pain Upper: 4 people, 17.39%
Pain: 2 people, 8.70%
High Blood Pressure: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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