Nitrostat and Septra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrostat (nitroglycerin) and Septra (sulfamethoxazole; trimethoprim). Common drug interactions include malaise among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrostat and Septra. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

On Jul, 14, 2026

33 people who take Nitrostat and Septra together, and have interactions are studied.

What are the common drug interactions of Nitrostat and Septra, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)
Abnormal dreams
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Asthenia (weakness)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

Asthenia (weakness)
Abdominal pain upper
Lung disorder (lung disease)
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain
Acute myocardial infarction (acute heart attack)
Adverse event
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)

What are the common drug interactions of Nitrostat and Septra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cardiac arrest
Acute myocardial infarction (acute heart attack)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arrhythmia (irregular heartbeat)
Asthma
Blindness
Bradycardia (abnormally slow heart action)
Cardiac murmur (an heart sound in valve abnormality)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Distress

50-59:

Renal hypertension (high blood pressure caused by the kidneys hormonal response)
Asthenia (weakness)
Body temperature increased
Lung disorder (lung disease)
Chronic kidney disease
Glomerulonephritis membranous (nephritis with inflammation of the capillary loops in the renal glomeruli)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

60+:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Asthenia (weakness)
Cardiac failure congestive
Chronic kidney disease
Diarrhoea
Dizziness
Gait disturbance
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Pain: 9 people, 27.27%
Sleep Disorder: 4 people, 12.12%
Joint Pain: 3 people, 9.09%
Neuropathy Peripheral (surface nerve damage): 3 people, 9.09%
Neuralgia (pain in one or more nerves): 3 people, 9.09%
Cough: 3 people, 9.09%
Nausea (feeling of having an urge to vomit): 3 people, 9.09%
Diarrhea: 3 people, 9.09%
Inflammation: 3 people, 9.09%
High Blood Pressure: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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