Nitrostat and Tradjenta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nitrostat (nitroglycerin) and Tradjenta (linagliptin). Common drug interactions include spinal fracture among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Nitrostat and Tradjenta. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.
What is Nitrostat?
Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.
What is Tradjenta?
Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.
94 people who take Nitrostat and Tradjenta together, and have interactions are studied.

What are the common drug interactions of Nitrostat and Tradjenta, by gender? *:
female:
- Spinal fracture (fracture in one of vertebrae)
- Urinary tract infection
- Cervix carcinoma (cancer of cervix)
- Abdominal pain
- Aphthous ulcer (mouth ulcer)
- Chronic respiratory failure
- Device related infection
- Disease progression
- Dizziness
- Drug ineffective
male:
- Chronic kidney disease
- Blood glucose increased
- Blood calcium increased
- Cardiac failure congestive
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Malaise (a feeling of general discomfort or uneasiness)
- Oxygen saturation decreased
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Stress
- Urinary tract infection
What are the common drug interactions of Nitrostat and Tradjenta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Nephropathy (damage to or disease of a kidney)
50-59:
- Depression
- Device related infection
- Diabetes mellitus inadequate control
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Dizziness
- Drug hypersensitivity
- Drug ineffective
- Drug level decreased
- Dyspnoea (difficult or laboured respiration)
- Essential hypertension (primary hypertension)
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Depression
- Blood calcium increased
- Cardiac disorder
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Constipation
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Malaise (a feeling of general discomfort or uneasiness)
- Oxygen saturation decreased
What are the existing conditions these people have? *
- High Blood Cholesterol: 26 people, 27.66%
- High Blood Pressure: 26 people, 27.66%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 25 people, 26.60%
- Pain: 20 people, 21.28%
- Type 2 Diabetes: 17 people, 18.09%
- Gout (uric acid crystals building up in the body): 14 people, 14.89%
- Hyperkalemia (damage to or disease of the kidney): 13 people, 13.83%
- Asthma: 10 people, 10.64%
- Depression: 10 people, 10.64%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 9.57%
* Approximation only. Some reports may have incomplete information.
Do you take Nitrostat and Tradjenta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nitrostat and Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nitrostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitrostat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tradjenta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nitroglycerin and linagliptin (the active ingredients of Nitrostat and Tradjenta, respectively), and Nitrostat and Tradjenta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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