Norco and Ocuflox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norco (acetaminophen; hydrocodone bitartrate) and Ocuflox (ofloxacin). Common drug interactions include conjunctival filtering bleb leak among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Norco and Ocuflox. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.

What is Ocuflox?

Ocuflox has active ingredients of ofloxacin. eHealthMe is studying from 492 Ocuflox users. Check the latest studies of Ocuflox.

On Jul, 17, 2026

13 people who take Norco and Ocuflox together, and have interactions are studied.

What are the common drug interactions of Norco and Ocuflox, by gender? *:

female:

Conjunctival filtering bleb leak (blister of conjunctiva leaks)
Device dislocation
Hypotony of eye (low intraocular pressure (iop))
Alopecia (absence of hair from areas of the body)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cough
Fatigue (feeling of tiredness)
Memory impairment
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Peripheral swelling

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Genotype drug resistance test positive
Headache (pain in head)
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Tooth fracture
Tooth loss
Weight decreased

What are the common drug interactions of Norco and Ocuflox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Dysstasia (difficulty in standing)
Emotional distress
Forearm fracture (fracture in between wrist to elbow)
Gait disturbance
Genotype drug resistance test positive
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Conjunctival filtering bleb leak (blister of conjunctiva leaks)
Device dislocation
Productive cough
Pulmonary thrombosis (scarring in the lungs)
Somnolence (a state of near-sleep, a strong desire for sleep)
Stress
Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
Visual field defect
Visual impairment
Carotid artery stenosis (narrowing of carotid artery)

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 30.77%
High Blood Cholesterol: 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Depression: 3 people, 23.08%
Insomnia (sleeplessness): 3 people, 23.08%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 15.38%
Faeces Hard: 2 people, 15.38%
Hypersensitivity: 2 people, 15.38%
Visual Impairment: 2 people, 15.38%
Hair Loss: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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