Talwin and Norco drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Talwin (pentazocine lactate) and Norco (acetaminophen; hydrocodone bitartrate). Common drug interactions include drug hypersensitivity among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Talwin and Norco. It is created by eHealthMe based on reports of 7 people who take the same drugs from the FDA, and is updated regularly.

What is Talwin?

Talwin has active ingredients of pentazocine lactate. It is often used in pain. eHealthMe is studying from 893 Talwin users. Check the latest studies of Talwin.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,060 Norco users. Check the latest studies of Norco.

On Aug, 18, 2025

7 people who take Talwin and Norco together, and have interactions are studied.

What are the common drug interactions of Talwin and Norco, by gender? *:

female:

Drug hypersensitivity
Convulsive threshold lowered
Diarrhoea
Activities of daily living impaired
Adjustment disorder
Affect lability (emotional incontinence)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anticonvulsant drug level above therapeutic
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)

male:

Anaemia (lack of blood)
Fall
Femoral neck fracture (neck of femur bone fracture)
Hepatic steatosis (fatty liver disease)
Hepatomegaly (abnormal enlargement of the liver)
Leukopenia (less number of white blood cells in blood)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Rib fracture
Splenomegaly (enlargement of spleen)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Talwin and Norco, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Urinary incontinence (inability to control the flow of urine and involuntary urination)
Activities of daily living impaired
Adjustment disorder
Affect lability (emotional incontinence)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anticonvulsant drug level above therapeutic
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)

50-59:

Convulsive threshold lowered
Diarrhoea
Drug hypersensitivity

60+:

Drug hypersensitivity
Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Fall
Femoral neck fracture (neck of femur bone fracture)
Hepatic steatosis (fatty liver disease)
Hepatomegaly (abnormal enlargement of the liver)
Leukopenia (less number of white blood cells in blood)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Rib fracture

* Approximation only. Some reports may have incomplete information.

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