Norepinephrine bitartrate and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norepinephrine bitartrate (norepinephrine bitartrate) and Midazolam (midazolam). Common drug interactions include muscular weakness among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Norepinephrine bitartrate and Midazolam. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Norepinephrine bitartrate?

Norepinephrine bitartrate has active ingredients of norepinephrine bitartrate. eHealthMe is studying from 2,370 Norepinephrine bitartrate users. Check the latest studies of Norepinephrine bitartrate.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

98 people who take Norepinephrine bitartrate and Midazolam together, and have interactions are studied.

Norepinephrine bitartrate and Midazolam drug interactions.

What are the common drug interactions of Norepinephrine Bitartrate and Midazolam, by gender? *:

female:

Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Postmenopausal haemorrhage (post-menopausal bleeding)
Pyrexia (fever)
Vomiting
Weight decreased
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Cardiogenic shock (inadequate circulation of blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

male:

Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Respiratory distress (difficulty in breathing)
Hypotension (abnormally low blood pressure)
Drug ineffective
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Low birth weight baby
Premature baby
Radiation pneumonitis (inflammation of lung due to radiation)
Anaphylactic reaction (serious allergic reaction)

What are the common drug interactions of Norepinephrine Bitartrate and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Lung disorder (lung disease)
Propofol infusion syndrome

30-39:

Maternal exposure during delivery (use of substance during pregnancy)
Maternal exposure during pregnancy (use of substance during pregnancy)
Premature delivery
Drug ineffective

40-49:

Alanine aminotransferase increased
Amylase increased
Blood creatine phosphokinase increased
Blood lactate dehydrogenase increased
Blood potassium increased
Hypotension (abnormally low blood pressure)
Myoglobin urine present
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Troponin increased

50-59:

Blood creatinine increased
Brain natriuretic peptide increased
Cardiac arrest
Cardiac failure
Cardiotoxicity (damage to the heart muscle)
Coronary artery stenosis (narrowing of coronary artery)
Diabetic macroangiopathy (fat and blood clots build up in the large blood vessels due to diabetes)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram st segment depression
Electrolyte imbalance

60+:

Pneumonia
Overdose
Anaphylactic reaction (serious allergic reaction)
Pyrexia (fever)
Acute respiratory failure
Cardiac failure acute
Hypoxia (low oxygen in tissues)
Abdominal pain
Abdominal pain upper
Adverse reaction

What are the existing conditions these people have? *

Hypotension (abnormally low blood pressure): 30 people, 30.61%
Sedation: 23 people, 23.47%
High Blood Pressure: 16 people, 16.33%
Stress And Anxiety: 16 people, 16.33%
Hypotonia (low muscle tone): 15 people, 15.31%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 15 people, 15.31%
Depression: 14 people, 14.29%
Septic Shock (shock due to blood infection): 11 people, 11.22%
Sepsis (a severe blood infection that can lead to organ failure and death): 10 people, 10.20%
Anaesthesia: 9 people, 9.18%

* Approximation only. Some reports may have incomplete information.

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