Norethindrone and Apixaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norethindrone (norethindrone) and Apixaban (apixaban). Common drug interactions include dyspnoea among females.

The phase IV clinical study analyzes what interactions people have when they take Norethindrone and Apixaban. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Norethindrone?

Norethindrone has active ingredients of norethindrone. It is often used in birth control. eHealthMe is studying from 1,610 Norethindrone users. Check the latest studies of Norethindrone.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.



On Jul, 30, 2026

11 people who take Norethindrone and Apixaban together, and have interactions are studied.

Norethindrone and Apixaban drug interactions.

What are the common drug interactions of Norethindrone and Apixaban, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pyrexia (fever)
  3. Hypersensitivity
  4. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  5. Lethargy (tiredness)
  6. Pruritus (severe itching of the skin)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

male:

n/a

What are the common drug interactions of Norethindrone and Apixaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Disease progression
  2. Dysmenorrhoea (painful menstruation)
  3. Dyspnoea (difficult or laboured respiration)
  4. General physical health deterioration (weak health status)
  5. Headache (pain in head)
  6. Hypoxia (low oxygen in tissues)
  7. Lung disorder (lung disease)
  8. Migraine (headache)
  9. Nausea (feeling of having an urge to vomit)
  10. Oxygen saturation decreased

20-29:

n/a

30-39:

  1. Pyrexia (fever)
  2. Pruritus (severe itching of the skin)
  3. Vomiting
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Chest pain
  9. Emotional distress
  10. Pain

40-49:

n/a

50-59:

  1. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)

60+:

n/a

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 5 people, 45.45%
  2. Nausea (feeling of having an urge to vomit): 4 people, 36.36%
  3. Iron Deficiency Anaemia: 4 people, 36.36%
  4. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 36.36%
  5. Abnormal Faeces (abnormal stool): 4 people, 36.36%
  6. Cystic Fibrosis (disease of the secretary glands): 3 people, 27.27%
  7. Vitamin B12 Deficiency: 2 people, 18.18%
  8. Anaemia Vitamin B12 Deficiency: 2 people, 18.18%
  9. Adverse Drug Reaction: 2 people, 18.18%
  10. Pulmonary Thrombosis (scarring in the lungs): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Norethindrone and Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norethindrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norethindrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Apixaban and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on norethindrone and apixaban (the active ingredients of Norethindrone and Apixaban, respectively), and Norethindrone and Apixaban (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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