Norplant and Dilantin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norplant (levonorgestrel) and Dilantin (phenytoin sodium). Common drug interactions include amenorrhoea among females.

The phase IV clinical study analyzes what interactions people have when they take Norplant and Dilantin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Norplant?

Norplant has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 6,430 Norplant users. Check the latest studies of Norplant.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

On Jul, 09, 2026

22 people who take Norplant and Dilantin together, and have interactions are studied.

Norplant and Dilantin drug interactions.

What are the common drug interactions of Norplant and Dilantin, by gender? *:

female:

Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
Abdominal distension
Abdominal pain
Abdominal tenderness
Abortion induced (medically referred abortion)
Abortion spontaneous (naturally occurring miscarriage)
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Agitation (state of anxiety or nervous excitement)
Alcohol abuse

male:

n/a

What are the common drug interactions of Norplant and Dilantin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Intermenstrual bleeding
Pulmonary embolism (blockage of the main artery of the lung)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Abortion induced (medically referred abortion)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Drug ineffective

20-29:

Pain in limb
Swelling
Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
Oedema (fluid collection in tissue)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Complication of drug device removal
Application site reaction
Chest pain
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)

30-39:

Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Anxiety
Application site reaction
Back pain
Bone pain
Breast cancer female
Breast induration
Breast pain

40-49:

n/a

50-59:

n/a

60+:

n/a

* Approximation only. Some reports may have incomplete information.

Do you take Norplant and Dilantin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously