Northera and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Northera (droxidopa) and Senna (senna). Common drug interactions include chest discomfort among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Northera and Senna. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 31, 2026

77 people who take Northera and Senna together, and have interactions are studied.

What are the common drug interactions of Northera and Senna, by gender? *:

female:

Chest discomfort
Dehydration (dryness resulting from the removal of water)
Failure to thrive (inadequate weight gain and physical growth in children)
Feeling hot
Hypokalaemia (low potassium)
Rash
Asthenia (weakness)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dizziness
Drug ineffective

male:

Death
Fall
Freezing phenomenon
Hypoacusis (loss of hearing)
Hallucination (an experience involving the perception of something not present)
Urinary tract infection
Pneumonia
Dizziness
Asthenia (weakness)
Memory impairment

What are the common drug interactions of Northera and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Drug ineffective
Muscle twitching
Blood sodium decreased
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Loss of consciousness

50-59:

Loss of consciousness
Blood pressure decreased
Blood pressure immeasurable
Hypertension (high blood pressure)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
Therapeutic response decreased (less preventive response)
Blood pressure increased
Cardiac arrest
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

Death
Fall
Nausea (feeling of having an urge to vomit)
Restlessness (not able to rest)
Gait disturbance
Asthenia (weakness)
Bladder disorder
Cerebral haemorrhage (bleeding within the brain)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Headache (pain in head)

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 35 people, 45.45%
Parkinson's Disease: 34 people, 44.16%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 12 people, 15.58%
Hypotension (abnormally low blood pressure): 8 people, 10.39%
Dizziness: 7 people, 9.09%
Hallucinations (sensations that appear real but are created by your mind): 6 people, 7.79%
Pain: 5 people, 6.49%
Delusion (a false belief or opinion): 5 people, 6.49%

* Approximation only. Some reports may have incomplete information.

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