Nortriptyline hydrochloride and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nortriptyline hydrochloride (nortriptyline hydrochloride) and Ms contin (morphine sulfate). Common drug interactions include diarrhoea among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Nortriptyline hydrochloride and Ms contin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Nortriptyline hydrochloride?

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,817 Nortriptyline hydrochloride users. Check the latest studies of Nortriptyline hydrochloride.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.



On Jul, 10, 2026

14 people who take Nortriptyline hydrochloride and Ms contin together, and have interactions are studied.

Nortriptyline hydrochloride and Ms contin drug interactions.

What are the common drug interactions of Nortriptyline Hydrochloride and Ms Contin, by gender? *:

female:

  1. Diarrhoea
  2. Dehydration (dryness resulting from the removal of water)
  3. Hypertension (high blood pressure)
  4. Anger
  5. Anxiety
  6. Confusion
  7. Disturbance in attention
  8. Drug dependence
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Haematemesis (vomiting of blood)

male:

  1. Cardiac failure congestive
  2. Dyspnoea (difficult or laboured respiration)
  3. Concussion (short loss of normal brain function in response to a head injury)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dry mouth
  6. Fall
  7. Headache (pain in head)
  8. Hypertension (high blood pressure)
  9. Injury
  10. Joint injury

What are the common drug interactions of Nortriptyline Hydrochloride and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardiac failure congestive
  2. Dyspnoea (difficult or laboured respiration)
  3. Fluid retention (an abnormal accumulation of fluid in the blood)
  4. Weight increased
  5. Urinary tract disorder

50-59:

  1. Head injury
  2. Chest pain
  3. Concussion (short loss of normal brain function in response to a head injury)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dry mouth
  6. Electrocardiogram qt prolonged
  7. Fall
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Hyperhidrosis (abnormally increased sweating)

60+:

  1. Diarrhoea

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 2 people, 14.29%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.14%
  3. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 7.14%
  4. Iron Overload: 1 person, 7.14%
  5. Hypersensitivity: 1 person, 7.14%
  6. Elevated Mood: 1 person, 7.14%
  7. Depression: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nortriptyline hydrochloride and Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nortriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nortriptyline hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride and morphine sulfate (the active ingredients of Nortriptyline hydrochloride and Ms contin, respectively), and Nortriptyline hydrochloride and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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