Nortriptyline hydrochloride and Sumatriptan succinate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nortriptyline hydrochloride (nortriptyline hydrochloride) and Sumatriptan succinate (sumatriptan succinate). Common drug interactions include headache among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Nortriptyline hydrochloride and Sumatriptan succinate. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Nortriptyline hydrochloride?

Nortriptyline hydrochloride has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,817 Nortriptyline hydrochloride users. Check the latest studies of Nortriptyline hydrochloride.

What is Sumatriptan succinate?

Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.

On Jul, 10, 2026

58 people who take Nortriptyline hydrochloride and Sumatriptan succinate together, and have interactions are studied.

Nortriptyline hydrochloride and Sumatriptan succinate drug interactions.

What are the common drug interactions of Nortriptyline Hydrochloride and Sumatriptan Succinate, by gender? *:

female:

Headache (pain in head)
Sinusitis (inflammation of sinus)
Anxiety
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Stress
Arthralgia (joint pain)
Ear infection
Herpes zoster
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

Blood pressure increased
Cardiomegaly (increased size of heart than normal)
Pulmonary mass
Respiratory failure (inadequate gas exchange by the respiratory system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tension headache
Cellulitis (infection under the skin)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)

What are the common drug interactions of Nortriptyline Hydrochloride and Sumatriptan Succinate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Infection
Anxiety
Application site reaction
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Binge drinking (excessive alcohol use)
Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
Bipolar disorder (mood disorder)
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)

30-39:

Alopecia (absence of hair from areas of the body)

40-49:

Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Abdominal pain
Accidental exposure
Anxiety
Arthralgia (joint pain)
Blood iron decreased
Drug ineffective
Headache (pain in head)
Hot flush (sudden feelings of heat)

50-59:

Blood glucose decreased
Impaired gastric emptying
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dizziness
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Fall
Infusion related reaction
Kidney infection
Loss of consciousness

60+:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abdominal distension
Limb injury
Lower limb fracture
Mass
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Oesophageal disorder (disease of oesophagus)
Respiratory disorder (respiratory disease)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 25.86%
Immunodeficiency Common Variable: 15 people, 25.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 20.69%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 11 people, 18.97%
Pain: 4 people, 6.90%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.90%
Headache (pain in head): 4 people, 6.90%
Drowsiness: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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