Norvir and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvir (ritonavir) and Elavil (amitriptyline hydrochloride). Common drug interactions include abdominal pain among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Norvir and Elavil. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Norvir?

Norvir has active ingredients of ritonavir. It is often used in hiv infection. eHealthMe is studying from 24,973 Norvir users. Check the latest studies of Norvir.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.



On Aug, 02, 2026

55 people who take Norvir and Elavil together, and have interactions are studied.

Norvir and Elavil drug interactions.

What are the common drug interactions of Norvir and Elavil, by gender? *:

female:

  1. Abdominal pain
  2. Abdominal pain upper
  3. Abnormal faeces (abnormal stool)
  4. Acne (skin problems that cause pimples)
  5. Anal fissure
  6. Anal fungal infection
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Arthralgia (joint pain)
  9. Asthenia (weakness)
  10. Back pain

male:

  1. Emotional distress
  2. Pain
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  5. Acute sinusitis
  6. Blood sodium decreased
  7. Haemoglobin decreased
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Abdominal distension
  10. Blood triglycerides increased

What are the common drug interactions of Norvir and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Face oedema (swelling of face)
  2. Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

  1. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  2. Postural hypotension

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Blood sodium decreased
  3. Pancreatitis (inflammation of pancreas)
  4. Abdominal distension
  5. Blood triglycerides increased
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Haemoglobin decreased
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Injection site induration
  10. Injection site pain

50-59:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Asthenia (weakness)
  4. Encephalopathy (functioning of the brain is affected by some agent or condition)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  7. Acute sinusitis
  8. Renal failure acute (rapid kidney dysfunction)
  9. Anxiety
  10. Chronic kidney disease

60+:

  1. Anxiety
  2. Bone density decreased
  3. Hyperlipidaemia (presence of excess lipids in the blood)
  4. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  5. Chronic kidney disease
  6. Emotional distress
  7. Pain
  8. Diarrhoea
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Diabetes: 6 people, 10.91%
  2. Pain: 5 people, 9.09%
  3. Neuropathy Peripheral (surface nerve damage): 5 people, 9.09%
  4. Hypersensitivity: 5 people, 9.09%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.09%
  6. High Blood Pressure: 5 people, 9.09%
  7. Vulvovaginal Mycotic Infection (vulvovaginal fungal infection): 3 people, 5.45%
  8. High Blood Cholesterol: 3 people, 5.45%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 5.45%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Norvir and Elavil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Norvir and Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norvir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Elavil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ritonavir and amitriptyline hydrochloride (the active ingredients of Norvir and Elavil, respectively), and Norvir and Elavil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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