Norvir and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvir (ritonavir) and Sumatriptan (sumatriptan succinate). Common drug interactions include anhedonia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Norvir and Sumatriptan. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Norvir?

Norvir has active ingredients of ritonavir. It is often used in hiv infection. eHealthMe is studying from 24,973 Norvir users. Check the latest studies of Norvir.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.



On Jul, 13, 2026

25 people who take Norvir and Sumatriptan together, and have interactions are studied.

Norvir and Sumatriptan drug interactions.

What are the common drug interactions of Norvir and Sumatriptan, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Chronic kidney disease
  6. Depression
  7. Osteoporosis (bones weak and more likely to break)
  8. Acidosis hyperchloraemic (increased acidity in the blood and other body tissue with decrease in plasma bicarbonate concentration)
  9. Asthenia (weakness)
  10. Bone density decreased

male:

  1. Emotional distress
  2. Pain
  3. Renal impairment (severely reduced kidney function)
  4. Arthralgia (joint pain)
  5. Blood creatinine increased
  6. Multiple fractures
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Depression
  9. Gait disturbance
  10. Headache (pain in head)

What are the common drug interactions of Norvir and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Depression
  4. Emotional distress
  5. Lethargy (tiredness)
  6. Pain
  7. Quality of life decreased
  8. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

30-39:

  1. Osteonecrosis (death of bone)
  2. Arthralgia (joint pain)
  3. Hip fracture
  4. Bone density decreased
  5. Emotional distress
  6. Pain
  7. Anxiety
  8. Depression
  9. Diarrhoea
  10. Femur fracture

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Renal impairment (severely reduced kidney function)
  7. Bone density decreased
  8. Multiple fractures
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Osteoporosis (bones weak and more likely to break)

50-59:

  1. Anxiety
  2. Bone density decreased
  3. Decreased activity
  4. Depression
  5. Fracture
  6. Mania (a state of abnormally elevated or irritable mood)
  7. Nephropathy (damage to or disease of a kidney)
  8. Osteoporosis (bones weak and more likely to break)
  9. Quality of life decreased
  10. Renal injury (kidney injury)

60+:

  1. Abdominal pain upper

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 12.00%
  2. Stress And Anxiety: 2 people, 8.00%
  3. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 8.00%
  4. Irritable Bowel Syndrome: 2 people, 8.00%
  5. Insomnia (sleeplessness): 2 people, 8.00%
  6. Inflammatory Pain: 2 people, 8.00%
  7. Depression: 2 people, 8.00%
  8. Bacterial Infection: 2 people, 8.00%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.00%
  10. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Norvir and Sumatriptan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Norvir and Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norvir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sumatriptan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ritonavir and sumatriptan succinate (the active ingredients of Norvir and Sumatriptan, respectively), and Norvir and Sumatriptan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: