Novalgin and Vitamin b1 drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Novalgin (metamizole) and Vitamin b1 (thiamine). Common drug interactions include sepsis among females and alopecia among males.
The phase IV clinical study analyzes what interactions people have when they take Novalgin and Vitamin b1. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Novalgin?
Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.
What is Vitamin b1?
Vitamin b1 has active ingredients of thiamine. It is often used in fatigue. eHealthMe is studying from 4,662 Vitamin b1 users. Check the latest studies of Vitamin b1.
33 people who take Novalgin and Vitamin b1 together, and have interactions are studied.

What are the common drug interactions of Novalgin and Vitamin B1, by gender? *:
female:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Death
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Ascites (accumulation of fluid in the abdominal cavity)
- Cardiac failure
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- General physical health deterioration (weak health status)
male:
- Alopecia (absence of hair from areas of the body)
- Blood bilirubin increased
- Incisional hernia (hernia caused by an incompletely-healed surgical wound)
- Insomnia (sleeplessness)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Mucosal inflammation (infection of mucous membrane)
- Nail bed inflammation (infection of nail bed)
- Nausea (feeling of having an urge to vomit)
- Oedema peripheral (superficial swelling)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
What are the common drug interactions of Novalgin and Vitamin B1, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
40-49:
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Hypernatraemia (an abnormally high plasma concentration of sodium ions)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Polyuria (production of too much dilute urine)
50-59:
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Ascites (accumulation of fluid in the abdominal cavity)
60+:
- Alopecia (absence of hair from areas of the body)
- Blood bilirubin increased
- Incisional hernia (hernia caused by an incompletely-healed surgical wound)
- Insomnia (sleeplessness)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Mucosal inflammation (infection of mucous membrane)
- Nail bed inflammation (infection of nail bed)
- Nausea (feeling of having an urge to vomit)
- Oedema peripheral (superficial swelling)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
What are the existing conditions these people have? *
- High Blood Pressure: 24 people, 72.73%
- Cardiac Failure: 24 people, 72.73%
- Nausea (feeling of having an urge to vomit): 24 people, 72.73%
- Infection: 24 people, 72.73%
- Constipation: 19 people, 57.58%
- Iron Deficiency: 14 people, 42.42%
- Gallstones (stone formation by bile component): 14 people, 42.42%
- Liver Disorder (liver diseases): 14 people, 42.42%
- Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 14 people, 42.42%
- Nasopharyngitis (inflammation of the nasopharynx): 14 people, 42.42%
* Approximation only. Some reports may have incomplete information.
Do you take Novalgin and Vitamin b1?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Novalgin (10,177 reports)
- Vitamin b1 (4,662 reports)
Browse all drug interactions of Novalgin and Vitamin b1:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Novalgin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vitamin b1:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Novalgin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vitamin b1 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metamizole and thiamine (the active ingredients of Novalgin and Vitamin b1, respectively), and Novalgin and Vitamin b1 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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