Novolin r and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novolin r (insulin recombinant purified human) and Cyclophosphamide (cyclophosphamide). Common drug interactions include septic shock among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Novolin r and Cyclophosphamide. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Novolin r?

Novolin r has active ingredients of insulin recombinant purified human. It is often used in type 1 diabetes. eHealthMe is studying from 4,568 Novolin r users. Check the latest studies of Novolin r.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.



On Jul, 12, 2026

27 people who take Novolin r and Cyclophosphamide together, and have interactions are studied.

Novolin r and Cyclophosphamide drug interactions.

What are the common drug interactions of Novolin R and Cyclophosphamide, by gender? *:

female:

  1. Septic shock (shock due to blood infection)
  2. Angioimmunoblastic t-cell lymphoma (mature t-cell cancer of the blood or lymph vessel)
  3. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  4. Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
  5. Liver disorder (liver diseases)
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
  8. Systemic candida (whole body fungal infection)
  9. Alopecia (absence of hair from areas of the body)
  10. Death

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Idiopathic pulmonary fibrosis (chronic lung disease)
  4. Interstitial lung disease
  5. Death
  6. Hypoproteinaemia (too little prolactin circulating in the blood)
  7. Bacteraemia (presence of bacteria in the blood)
  8. Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
  9. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  10. Cytomegalovirus antigen positive

What are the common drug interactions of Novolin R and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hypoproteinaemia (too little prolactin circulating in the blood)

20-29:

n/a

30-39:

  1. Alopecia (absence of hair from areas of the body)
  2. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  3. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  4. Escherichia infection (bacterial infection by escherichia coli)
  5. Klebsiella infection
  6. Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)

40-49:

  1. Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
  2. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  3. Cytomegalovirus antigen positive
  4. Diarrhoea
  5. Weight decreased

50-59:

  1. Pneumonia
  2. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
  3. Idiopathic pulmonary fibrosis (chronic lung disease)
  4. Interstitial lung disease
  5. Lymphoma (cancer that begins in immune system cells)
  6. Septic shock (shock due to blood infection)
  7. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Platelet count decreased

60+:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Systemic candida (whole body fungal infection)
  4. Death
  5. Altered state of consciousness (altered state of mind)
  6. Epstein-barr virus infection
  7. Pneumonia
  8. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Angioimmunoblastic t-cell lymphoma (mature t-cell cancer of the blood or lymph vessel)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 22.22%
  2. Septic Shock (shock due to blood infection): 4 people, 14.81%
  3. Infection: 4 people, 14.81%
  4. Angioimmunoblastic T-Cell Lymphoma (mature t-cell cancer of the blood or lymph vessel): 4 people, 14.81%
  5. Tuberculous Pleurisy (an inflammation of lung covering plura by mycobacterium tuberculosis): 3 people, 11.11%
  6. Diabetes Mellitus Inadequate Control: 3 people, 11.11%
  7. Breast Cancer Female: 3 people, 11.11%
  8. Aplastic Anemia: 3 people, 11.11%
  9. Adverse Event: 3 people, 11.11%
  10. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Novolin r and Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Novolin r:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Novolin r and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyclophosphamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on insulin recombinant purified human and cyclophosphamide (the active ingredients of Novolin r and Cyclophosphamide, respectively), and Novolin r and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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