Noxafil and Colistimethate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Noxafil (posaconazole) and Colistimethate (colistimethate sodium). Common drug interactions include dysphonia among females and influenza among males.

The phase IV clinical study analyzes what interactions people have when they take Noxafil and Colistimethate. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Noxafil?

Noxafil has active ingredients of posaconazole. eHealthMe is studying from 5,919 Noxafil users. Check the latest studies of Noxafil.

What is Colistimethate?

Colistimethate has active ingredients of colistimethate sodium. eHealthMe is studying from 1,502 Colistimethate users. Check the latest studies of Colistimethate.



On Aug, 03, 2026

25 people who take Noxafil and Colistimethate together, and have interactions are studied.

Noxafil and Colistimethate drug interactions.

What are the common drug interactions of Noxafil and Colistimethate, by gender? *:

female:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Sinusitis (inflammation of sinus)
  4. Sinus congestion (blockage of sinus)
  5. Acne (skin problems that cause pimples)
  6. Asthenia (weakness)
  7. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  8. Bacteraemia (presence of bacteria in the blood)
  9. Decreased appetite
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Influenza
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Hypervolaemia (abnormally increased volume of blood)
  4. Multi-organ failure (multisystem organ failure)
  5. Oedema (fluid collection in tissue)
  6. Oliguria (not enough urine)
  7. Abdominal pain upper
  8. Aggression
  9. Anxiety
  10. Cystic fibrosis (disease of the secretary glands)

What are the common drug interactions of Noxafil and Colistimethate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Aggression
  2. Anxiety
  3. Panic attack

20-29:

  1. Septic shock (shock due to blood infection)
  2. Venoocclusive liver disease (small veins in the liver are obstructed)
  3. Abdominal pain upper
  4. Arthralgia (joint pain)
  5. Cystic fibrosis (disease of the secretary glands)
  6. Dermatitis psoriasiform (large white or silver flakes on the skin)
  7. Eye abscess
  8. Forced expiratory volume decreased (decreased lung expired air volume)
  9. Hepatotoxicity (chemical-driven liver damage)
  10. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

30-39:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Sinusitis (inflammation of sinus)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Acne (skin problems that cause pimples)
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Sinus congestion (blockage of sinus)
  9. Vision blurred
  10. Acute lymphocytic leukaemia (cancer of the white blood cells)

40-49:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

50-59:

  1. Influenza
  2. Hospitalisation
  3. Skin lesion

60+:

  1. Asthenia (weakness)
  2. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  3. Oral fungal infection
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pneumonia
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Intervertebral disc protrusion (spinal disc protrusion)
  8. Intestinal haemorrhage (bleeding from intestine)
  9. Renal failure (kidney dysfunction)
  10. Bacteraemia (presence of bacteria in the blood)

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 14 people, 56.00%
  2. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 16.00%
  3. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 8.00%
  4. Diarrhea: 2 people, 8.00%
  5. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 2 people, 8.00%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.00%
  7. Bacteraemia (presence of bacteria in the blood): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Noxafil and Colistimethate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Noxafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colistimethate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Noxafil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colistimethate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on posaconazole and colistimethate sodium (the active ingredients of Noxafil and Colistimethate, respectively), and Noxafil and Colistimethate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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