Nplate and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nplate (romiplostim) and Lanoxin (digoxin). Common drug interactions include petechiae among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Nplate and Lanoxin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.



On Jul, 10, 2026

19 people who take Nplate and Lanoxin together, and have interactions are studied.

Nplate and Lanoxin drug interactions.

What are the common drug interactions of Nplate and Lanoxin, by gender? *:

female:

  1. Petechiae (a small red or purple spot caused by bleeding into the skin)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Arthralgia (joint pain)
  4. Cerebral infarction (less blood supply to brain resulting tissue damage)
  5. Groin pain
  6. Hypotension (abnormally low blood pressure)
  7. Leukocytosis (increased white blood cells)
  8. Platelet count decreased
  9. Urinary tract infection
  10. Abdominal pain

male:

  1. Abdominal pain
  2. Asthenia (weakness)
  3. Pain in extremity
  4. Platelet count decreased
  5. Pleural effusion (water on the lungs)
  6. Vomiting
  7. Abdominal distension
  8. Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
  9. Acute respiratory failure
  10. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)

What are the common drug interactions of Nplate and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abdominal distension
  2. Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
  3. Anaemia (lack of blood)
  4. Atelectasis (partial or complete collapse of the lung)
  5. Cardiac failure chronic
  6. Cardiac failure congestive
  7. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  8. Fungal infection
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)

60+:

  1. Abdominal pain
  2. Diarrhoea
  3. Groin pain
  4. Hypotension (abnormally low blood pressure)
  5. Urinary tract infection
  6. Abdominal pain upper
  7. Body temperature increased
  8. Chills (felling of cold)
  9. Death
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 16 people, 84.21%
  2. Autoimmune Thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia): 2 people, 10.53%
  3. Anaemia (lack of blood): 2 people, 10.53%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Nplate and Lanoxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nplate and Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nplate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nplate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on romiplostim and digoxin (the active ingredients of Nplate and Lanoxin, respectively), and Nplate and Lanoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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