Nplate and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nplate (romiplostim) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include platelet count decreased among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Nplate and Valacyclovir. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 24, 2026

70 people who take Nplate and Valacyclovir together, and have interactions are studied.

Nplate and Valacyclovir drug interactions.

What are the common drug interactions of Nplate and Valacyclovir, by gender? *:

female:

Platelet count decreased
Skin disorder (skin disease)
Small cell lung cancer stage unspecified (lung cancer in unknown stage)
Sputum discoloured
Therapeutic response decreased (less preventive response)
Urticaria (rash of round, red welts on the skin that itch intensely)
White blood cell count decreased
White blood cell count increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Emphysematous cystitis (inflammation of the urinary bladder)

male:

Thrombocytopenia (decrease of platelets in blood)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Leukocytosis (increased white blood cells)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pseudohyperkalaemia (marked increase of in vitro serum potassium levels)
Purpura (purplish discoloration of the skin)
Septic shock (shock due to blood infection)
Urinary hesitation (difficulty in beginning the flow of urine)
Urinary tract obstruction
Volvulus (obstruction caused by twisting of the stomach or intestine)

What are the common drug interactions of Nplate and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Right ventricular failure (right half of the heart fails to work)

20-29:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Platelet count decreased

30-39:

n/a

40-49:

n/a

50-59:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Erythema multiforme (a type of hypersensitivity reaction)
Abdominal pain
Acute respiratory distress syndrome
Death
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

60+:

Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Enterocolitis infectious
Hypokalaemia (low potassium)
Influenza like illness
Leukocytosis (increased white blood cells)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pseudohyperkalaemia (marked increase of in vitro serum potassium levels)
Purpura (purplish discoloration of the skin)
Urinary hesitation (difficulty in beginning the flow of urine)

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 20 people, 28.57%
Pain: 19 people, 27.14%
Nausea (feeling of having an urge to vomit): 19 people, 27.14%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 18 people, 25.71%
Venoocclusive Disease (small veins in the liver are obstructed): 17 people, 24.29%
High Blood Pressure: 17 people, 24.29%
Fungal Infection: 17 people, 24.29%
Blood Disorder: 17 people, 24.29%
Abdominal Pain Upper: 17 people, 24.29%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 9 people, 12.86%

* Approximation only. Some reports may have incomplete information.

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