1. Home
  2. Analysis
  3. Nucala
  4. Colace

Nucala and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nucala (mepolizumab) and Colace (docusate ). Common drug interactions include dizziness among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Nucala and Colace. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Nucala?

Nucala has active ingredients of mepolizumab. eHealthMe is studying from 26,883 Nucala users. Check the latest studies of Nucala.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 08, 2026

12 people who take Nucala and Colace together, and have interactions are studied.

Nucala and Colace drug interactions.

What are the common drug interactions of Nucala and Colace, by gender? *:

female:

  1. Dizziness
  2. Abdominal discomfort
  3. Asthenia (weakness)
  4. Blood pressure increased
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Hypertension (high blood pressure)
  9. Pain
  10. Arthralgia (joint pain)

male:

  1. Anxiety
  2. Claustrophobia (fear of having no escape and being closed in small spaces)
  3. Conjunctivitis (pink eye)
  4. Decreased appetite
  5. Dyspnoea (difficult or laboured respiration)
  6. Insomnia (sleeplessness)
  7. Lacrimation increased
  8. Ocular hyperaemia (an abnormally large amount of blood in eye)
  9. Panic reaction
  10. Swelling face

What are the common drug interactions of Nucala and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Conjunctivitis (pink eye)
  2. Lacrimation increased
  3. Ocular hyperaemia (an abnormally large amount of blood in eye)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Dyspnoea (difficult or laboured respiration)
  2. Swelling face

60+:

  1. Anxiety
  2. Arthralgia (joint pain)
  3. Pain
  4. Pain in extremity
  5. Panic reaction
  6. Sluggishness (lacking alertness)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Claustrophobia (fear of having no escape and being closed in small spaces)
  9. Decreased appetite
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Asthma: 5 people, 41.67%
  2. Otitis (ear infection): 1 person, 8.33%
  3. Immunodeficiency Common Variable: 1 person, 8.33%
  4. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nucala and Colace?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nucala and Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nucala:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nucala and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mepolizumab and docusate (the active ingredients of Nucala and Colace, respectively), and Nucala and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.