Nuedexta and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuedexta (dextromethorphan hydrobromide; quinidine sulfate) and Botox (botulinum toxin type a). Common drug interactions include sinusitis among females and choking among males.

The phase IV clinical study analyzes what interactions people have when they take Nuedexta and Botox. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Nuedexta?

Nuedexta has active ingredients of dextromethorphan hydrobromide; quinidine sulfate. eHealthMe is studying from 3,781 Nuedexta users. Check the latest studies of Nuedexta.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

48 people who take Nuedexta and Botox together, and have interactions are studied.

What are the common drug interactions of Nuedexta and Botox, by gender? *:

female:

Sinusitis (inflammation of sinus)
Spinal fracture (fracture in one of vertebrae)
Asthenia (weakness)
Weight increased
Back pain
Blood iron decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)

male:

Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Vertigo positional
Gait disturbance
Headache (pain in head)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

What are the common drug interactions of Nuedexta and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Gait disturbance

40-49:

Fall
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Sinusitis (inflammation of sinus)
Spinal fracture (fracture in one of vertebrae)
Bladder disorder
Depression
Drug effect delayed
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)
Lower respiratory tract infection

50-59:

Breast mass
Drug ineffective
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Asthenia (weakness)
Balance disorder

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Therapeutic response unexpected
Weight increased
Vomiting
Dry mouth
Fatigue (feeling of tiredness)
Vertigo positional
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Coma (state of unconsciousness lasting more than six hours)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 25.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 20.83%
Immunodeficiency: 9 people, 18.75%
Primary Immunodeficiency Syndrome: 6 people, 12.50%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 6 people, 12.50%
Crying: 4 people, 8.33%
Stress And Anxiety: 3 people, 6.25%
Overdose: 3 people, 6.25%
Hypersensitivity: 3 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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