Nuedexta and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuedexta (dextromethorphan hydrobromide; quinidine sulfate) and Naltrexone (naltrexone). Common drug interactions include fall among females.

The phase IV clinical study analyzes what interactions people have when they take Nuedexta and Naltrexone. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Nuedexta?

Nuedexta has active ingredients of dextromethorphan hydrobromide; quinidine sulfate. eHealthMe is studying from 3,781 Nuedexta users. Check the latest studies of Nuedexta.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,835 Naltrexone users. Check the latest studies of Naltrexone.



On Aug, 05, 2026

13 people who take Nuedexta and Naltrexone together, and have interactions are studied.

Nuedexta and Naltrexone drug interactions.

What are the common drug interactions of Nuedexta and Naltrexone, by gender? *:

female:

  1. Fall
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  3. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Cervical cord compression (compression of spinal cord at site of cervical vertebrae)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Mobility decreased (ability to move is reduced)
  8. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  9. Vitamin b12 increased
  10. Abdominal pain

male:

n/a

What are the common drug interactions of Nuedexta and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Fall
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  3. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Cervical cord compression (compression of spinal cord at site of cervical vertebrae)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Mobility decreased (ability to move is reduced)
  8. Vitamin b12 increased
  9. Asthenia (weakness)
  10. Cervix disorder

60+:

n/a

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 92.31%
  2. Stress And Anxiety: 4 people, 30.77%
  3. Muscle Spasms (muscle contraction): 4 people, 30.77%
  4. Nausea (feeling of having an urge to vomit): 3 people, 23.08%
  5. Gait Disturbance: 2 people, 15.38%
  6. Nausea And Vomiting: 1 person, 7.69%
  7. High Blood Pressure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Nuedexta and Naltrexone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nuedexta and Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuedexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuedexta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naltrexone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dextromethorphan hydrobromide; quinidine sulfate and naltrexone (the active ingredients of Nuedexta and Naltrexone, respectively), and Nuedexta and Naltrexone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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