Nuvaring and Acyclovir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nuvaring (ethinyl estradiol; etonogestrel) and Acyclovir (acyclovir). Common drug interactions include pulmonary embolism among females.
The phase IV clinical study analyzes what interactions people have when they take Nuvaring and Acyclovir. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Nuvaring?
Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.
What is Acyclovir?
Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.
19 people who take Nuvaring and Acyclovir together, and have interactions are studied.

What are the common drug interactions of Nuvaring and Acyclovir, by gender? *:
female:
- Pulmonary embolism (blockage of the main artery of the lung)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- International normalised ratio increased
- Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
- Pulmonary infarction (death of a small area of lung)
- Skin wrinkling (wrinkle on skin)
- Blood homocysteine decreased
- Breast cancer
male:
n/a
What are the common drug interactions of Nuvaring and Acyclovir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abdominal pain upper
20-29:
- Cystitis (inflammation of the wall of the bladder)
- Headache (pain in head)
- Lymphopenia (an abnormally low level of lymphocytes in the blood)
- Nausea (feeling of having an urge to vomit)
- Abdominal pain
- Activated partial thromboplastin time prolonged
- Body temperature increased
- Bradycardia (abnormally slow heart action)
- Constipation
- Decreased appetite
30-39:
- Pulmonary embolism (blockage of the main artery of the lung)
- Thrombotic stroke (stroke due to clot formation)
40-49:
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Oropharyngeal pain
- International normalised ratio increased
- Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
- Pain in extremity
- Pulmonary infarction (death of a small area of lung)
- Skin wrinkling (wrinkle on skin)
- Activated partial thromboplastin time prolonged
- Blood homocysteine decreased
- Breast cancer
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Progressive Multiple Sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord): 2 people, 10.53%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
- Adverse Event: 2 people, 10.53%
- Seasonal Allergy (allergic condition due to certain season): 1 person, 5.26%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.26%
- Dysmenorrhea (painful menstruation): 1 person, 5.26%
- Drowsiness: 1 person, 5.26%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Nuvaring and Acyclovir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nuvaring and Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nuvaring:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nuvaring and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acyclovir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on ethinyl estradiol; etonogestrel and acyclovir (the active ingredients of Nuvaring and Acyclovir, respectively), and Nuvaring and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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