Nuvaring and Cytotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuvaring (ethinyl estradiol; etonogestrel) and Cytotec (misoprostol). Common drug interactions include maternal exposure during pregnancy among females.

The phase IV clinical study analyzes what interactions people have when they take Nuvaring and Cytotec. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

What is Cytotec?

Cytotec has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 5,812 Cytotec users. Check the latest studies of Cytotec.



On Jul, 26, 2026

12 people who take Nuvaring and Cytotec together, and have interactions are studied.

Nuvaring and Cytotec drug interactions.

What are the common drug interactions of Nuvaring and Cytotec, by gender? *:

female:

  1. Maternal exposure during pregnancy (use of substance during pregnancy)
  2. Hypotonia neonatal (low muscle tone in neonatal)
  3. Fall
  4. Loose tooth
  5. Oral disorder (mouth disease)
  6. Parasitic gastroenteritis (inflammation of the digestive tract by parasite infection)
  7. Pneumonia
  8. Tooth extraction
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Vomiting

male:

n/a

What are the common drug interactions of Nuvaring and Cytotec, by age (0-1 to 60+)? *:

0-1:

  1. Hypotonia neonatal (low muscle tone in neonatal)
  2. Neonatal disorder (disease of neonates)
  3. Nystagmus (a condition of involuntary eye movement)
  4. Respiratory disorder neonatal (disease of respiratory organs in a month old baby)
  5. Maternal exposure during pregnancy (use of substance during pregnancy)

2-9:

n/a

10-19:

n/a

20-29:

  1. Vomiting
  2. Maternal exposure during pregnancy (use of substance during pregnancy)
  3. Abortion spontaneous (naturally occurring miscarriage)
  4. Abortion induced (medically referred abortion)
  5. Parasitic gastroenteritis (inflammation of the digestive tract by parasite infection)

30-39:

n/a

40-49:

  1. Dental caries
  2. Dystonia (abnormal muscle tone)
  3. Facial bones fracture (bone fracture of face)
  4. Fall
  5. Pneumonia
  6. Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Labor Induction: 5 people, 41.67%
  2. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 4 people, 33.33%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 25.00%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%
  6. Pain: 1 person, 8.33%
  7. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 8.33%
  8. Abortion Induced (medically referred abortion): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nuvaring and Cytotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cytotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuvaring and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytotec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; etonogestrel and misoprostol (the active ingredients of Nuvaring and Cytotec, respectively), and Nuvaring and Cytotec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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