Nuvaring and Provera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuvaring (ethinyl estradiol; etonogestrel) and Provera (medroxyprogesterone acetate). Common drug interactions include pulmonary embolism among females.

The phase IV clinical study analyzes what interactions people have when they take Nuvaring and Provera. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

On Jul, 18, 2026

100 people who take Nuvaring and Provera together, and have interactions are studied.

What are the common drug interactions of Nuvaring and Provera, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Vomiting
Vitamin b12 deficiency
Anxiety
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Foot fracture
Uterine perforation (accidental puncture of the uterus)
Pleural effusion (water on the lungs)
Ligament rupture (tear in ligament)

male:

n/a

What are the common drug interactions of Nuvaring and Provera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Pulmonary embolism (blockage of the main artery of the lung)
Road traffic accident
Arthralgia (joint pain)
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Oedema peripheral (superficial swelling)
Osteitis (a general term for inflammation of bone)
Pain in extremity

20-29:

Pulmonary embolism (blockage of the main artery of the lung)
Nausea (feeling of having an urge to vomit)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pleural effusion (water on the lungs)
Vomiting
Blood cholesterol increased
Dehydration (dryness resulting from the removal of water)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pulmonary infarction (death of a small area of lung)
Loss of consciousness

30-39:

Foot fracture
Haemoglobin decreased
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Vomiting
Chest pain
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

40-49:

Abdominal pain
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Medical device discomfort (difficulty due to medical devices)
Pelvic pain
Uterine perforation (accidental puncture of the uterus)
Anxiety
Depressed mood
Depression
Emotional distress
Fear

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 17.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 15.00%
Depression: 6 people, 6.00%
Stress And Anxiety: 5 people, 5.00%
Heavy Or Prolong Menstrual Bleeding: 5 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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