Nuvaring and Temaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuvaring (ethinyl estradiol; etonogestrel) and Temaz (temazepam). Common drug interactions include deep vein thrombosis among females.

The phase IV clinical study analyzes what interactions people have when they take Nuvaring and Temaz. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

What is Temaz?

Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.



On Jul, 12, 2026

38 people who take Nuvaring and Temaz together, and have interactions are studied.

Nuvaring and Temaz drug interactions.

What are the common drug interactions of Nuvaring and Temaz, by gender? *:

female:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. International normalised ratio increased
  3. Mitral valve incompetence (inefficient heart valve)
  4. Muscle spasms (muscle contraction)
  5. Oedema peripheral (superficial swelling)
  6. Cellulitis (infection under the skin)
  7. Dysthymic disorder (mild chronic depression disorder)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Joint sprain (an injury to joint surrounding flexible fibres)

male:

n/a

What are the common drug interactions of Nuvaring and Temaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Alcohol abuse
  2. Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
  3. Borderline personality disorder
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Drug abuse
  6. Mitral valve incompetence (inefficient heart valve)
  7. Cellulitis (infection under the skin)
  8. Dysthymic disorder (mild chronic depression disorder)
  9. International normalised ratio increased
  10. Joint sprain (an injury to joint surrounding flexible fibres)

30-39:

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
  2. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  3. Nausea (feeling of having an urge to vomit)
  4. Night sweats (sweating in night)
  5. Pain in extremity
  6. Pancreatitis (inflammation of pancreas)
  7. Pelvic pain
  8. Pregnancy with contraceptive device
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Renal failure chronic (long lasting kidney dysfunction)

40-49:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. International normalised ratio increased
  3. Laryngitis (inflammation of the larynx)
  4. Muscle spasms (muscle contraction)
  5. Panic attack
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  8. Shoulder operation
  9. Sweat gland tumour
  10. Upper respiratory tract infection

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 23.68%
  2. Migraine (headache): 5 people, 13.16%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 10.53%
  4. Menstruation Irregular: 2 people, 5.26%
  5. Headache (pain in head): 2 people, 5.26%
  6. Depression: 2 people, 5.26%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 5.26%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Nuvaring and Temaz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nuvaring and Temaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuvaring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Temaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuvaring and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Temaz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; etonogestrel and temazepam (the active ingredients of Nuvaring and Temaz, respectively), and Nuvaring and Temaz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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