Nuvigil and Adipex-p drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuvigil (armodafinil) and Adipex-p (phentermine hydrochloride). Common drug interactions include obstructive sleep apnoea syndrome among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Nuvigil and Adipex-p. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

What is Adipex-p?

Adipex-p has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 2,718 Adipex-p users. Check the latest studies of Adipex-p.



On Jul, 14, 2026

24 people who take Nuvigil and Adipex-p together, and have interactions are studied.

Nuvigil and Adipex-p drug interactions.

What are the common drug interactions of Nuvigil and Adipex-P, by gender? *:

female:

  1. Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
  2. Pain
  3. Alopecia (absence of hair from areas of the body)
  4. Blood folate decreased
  5. Haemoglobin decreased
  6. Lymphocyte count decreased
  7. Mean cell volume increased (more than normal average red blood cell volume)
  8. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Pyrexia (fever)
  10. Red blood cell count decreased

male:

  1. Anxiety
  2. Choking (mechanical obstruction of the flow of air from the environment into the lungs)

What are the common drug interactions of Nuvigil and Adipex-P, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Altered state of consciousness (altered state of mind)
  2. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  3. Post-traumatic stress disorder
  4. Weight decreased

40-49:

  1. Ankle fracture
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
  4. Fall
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Hypersensitivity
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Throat tightness

50-59:

  1. Cyst (a closed sac)
  2. Renal disorder (kidney disease)
  3. Influenza
  4. Abdominal discomfort
  5. Anxiety
  6. Arthralgia (joint pain)
  7. Diarrhoea
  8. Fear
  9. Gastric ph decreased
  10. Gastritis (inflammation of stomach)

60+:

  1. Alopecia (absence of hair from areas of the body)
  2. Blood folate decreased
  3. White blood cell count decreased
  4. Balance disorder
  5. Confusional state
  6. Cough
  7. Diplopia (double vision)
  8. Dry skin
  9. Dysstasia (difficulty in standing)
  10. Fall

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 54.17%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 16.67%
  3. Pain: 2 people, 8.33%
  4. Drowsiness: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Nuvigil and Adipex-p?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nuvigil and Adipex-p:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuvigil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adipex-p:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuvigil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adipex-p and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on armodafinil and phentermine hydrochloride (the active ingredients of Nuvigil and Adipex-p, respectively), and Nuvigil and Adipex-p (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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