Nystatin and Evoxac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nystatin (nystatin) and Evoxac (cevimeline hydrochloride). Common drug interactions include urethral stenosis among females and aortic stenosis among males.

The phase IV clinical study analyzes what interactions people have when they take Nystatin and Evoxac. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Nystatin?

Nystatin has active ingredients of nystatin. It is often used in thrush. eHealthMe is studying from 33,568 Nystatin users. Check the latest studies of Nystatin.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

48 people who take Nystatin and Evoxac together, and have interactions are studied.

What are the common drug interactions of Nystatin and Evoxac, by gender? *:

female:

Urethral stenosis (narrowing of the urethra, may cause decreased urine output)
Urinary retention (the inability to completely or partially empty the bladder)
Vomiting
Chest pain
Gastritis (inflammation of stomach)
Sinus headache (headache caused by sinus infections)
Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia)
Altered state of consciousness (altered state of mind)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cystitis interstitial (unknown cause characterized by bladder pain)

male:

Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve incompetence
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinusitis (inflammation of sinus)
Skin ulcer
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive

What are the common drug interactions of Nystatin and Evoxac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal mass (localized enlargement or swelling in the human abdomen)
Activities of daily living impaired
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aphasia (damage to the parts of the brain that control language)
Arthralgia (joint pain)
Back pain
Balance disorder
Blood antidiuretic hormone decreased

50-59:

Chest wall mass
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Decreased appetite
Deformity (disfigurement)
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Early satiety (feeling full before completing a normal sized meal)

60+:

Cardiac failure congestive
Fall
Abdominal pain
Acquired oesophageal web (structural abnormalities in the oesophagus)
Altered state of consciousness (altered state of mind)
Anogenital warts
Anxiety
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve incompetence
Arthralgia (joint pain)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 10 people, 20.83%
Breast Cancer: 8 people, 16.67%
Multiple Myeloma (cancer of the plasma cells): 7 people, 14.58%
High Blood Pressure: 6 people, 12.50%
Pain: 5 people, 10.42%
Neuralgia (pain in one or more nerves): 5 people, 10.42%
Behcet's Syndrome (involves inflammation of the blood vessels): 5 people, 10.42%
Stress And Anxiety: 5 people, 10.42%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.42%
Depression: 5 people, 10.42%

* Approximation only. Some reports may have incomplete information.

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