Nystatin and Zemplar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nystatin (nystatin) and Zemplar (paricalcitol). Common drug interactions include hypoaesthesia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Nystatin and Zemplar. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Nystatin?

Nystatin has active ingredients of nystatin. It is often used in thrush. eHealthMe is studying from 33,567 Nystatin users. Check the latest studies of Nystatin.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.



On Jul, 04, 2026

59 people who take Nystatin and Zemplar together, and have interactions are studied.

Nystatin and Zemplar drug interactions.

What are the common drug interactions of Nystatin and Zemplar, by gender? *:

female:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Muscular weakness (muscle weakness)
  3. Oedema peripheral (superficial swelling)
  4. Chest pain
  5. Diarrhoea
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Fall
  8. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  9. Intervertebral disc protrusion (spinal disc protrusion)
  10. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Oedema (fluid collection in tissue)
  5. Pain in extremity
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Abdominal pain
  8. Angioedema (rapid swelling of the dermis)
  9. Blood pressure fluctuation
  10. Burning sensation

What are the common drug interactions of Nystatin and Zemplar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Gastritis (inflammation of stomach)
  2. Hypokalaemia (low potassium)
  3. Irritability
  4. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)

10-19:

  1. Renal transplant

20-29:

  1. Abscess oral (abscess in the mouth)
  2. Anaemia macrocytic (a macrocytic class of anaemia)
  3. Anxiety
  4. Aortic dilatation
  5. Arteriovenous fistula
  6. Arthralgia (joint pain)
  7. Back disorder
  8. Back pain
  9. Blood albumin decreased
  10. Blood bicarbonate decreased

30-39:

  1. Deformity (disfigurement)
  2. Device related infection
  3. Erythema (redness of the skin)
  4. Muscle tightness
  5. Muscular weakness (muscle weakness)
  6. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  7. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  8. Oedema peripheral (superficial swelling)
  9. Pain
  10. Pain in extremity

40-49:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Abdominal pain
  3. Angioedema (rapid swelling of the dermis)
  4. Arthralgia (joint pain)
  5. Blood pressure fluctuation
  6. Burning sensation
  7. Chest pain
  8. Dizziness
  9. Drug hypersensitivity
  10. Dysphagia (a condition in which swallowing is difficult or painful)

50-59:

  1. Chest pain
  2. Dry skin
  3. Emotional distress
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Joint contracture (a permanent shortening of a muscle or joint)
  6. Joint stiffness
  7. Mobility decreased (ability to move is reduced)
  8. Muscular weakness (muscle weakness)
  9. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  10. Oedema peripheral (superficial swelling)

60+:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Pain
  4. Pleural effusion (water on the lungs)
  5. Proteinuria (presence of protein in the urine)
  6. Anaemia macrocytic (a macrocytic class of anaemia)
  7. Arteriovenous fistula
  8. Back pain
  9. Carotid artery stenosis (narrowing of carotid artery)
  10. Cellulitis (infection under the skin)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 24 people, 40.68%
  2. High Blood Pressure: 18 people, 30.51%
  3. Pain: 15 people, 25.42%
  4. Diabetes: 13 people, 22.03%
  5. Stable Angina (a constant chest pain): 10 people, 16.95%
  6. Multiple Myeloma (cancer of the plasma cells): 8 people, 13.56%
  7. High Blood Cholesterol: 8 people, 13.56%
  8. Anaemia (lack of blood): 8 people, 13.56%
  9. Acute Kidney Failure: 6 people, 10.17%
  10. Swallowing Difficulty: 6 people, 10.17%

* Approximation only. Some reports may have incomplete information.

Do you take Nystatin and Zemplar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nystatin and Zemplar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nystatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zemplar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nystatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zemplar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nystatin and paricalcitol (the active ingredients of Nystatin and Zemplar, respectively), and Nystatin and Zemplar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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