Ocrevus and Asa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ocrevus (ocrelizumab) and Asa (aspirin). Common drug interactions include uhthoff's phenomenon among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Ocrevus and Asa. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

23 people who take Ocrevus and Asa together, and have interactions are studied.

What are the common drug interactions of Ocrevus and Asa, by gender? *:

female:

Uhthoff's phenomenon (heat intolerance)
Abscess limb (limb infection)
Gait disturbance
Hyperglycaemia (high blood sugar)
Mouth ulceration (mouth ulcers)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Tendonitis (a condition that causes pain and swelling of tendons)
Tooth abscess (pus formation in tooth)
Urinary tract infection
Vaginal infection

male:

Fatigue (feeling of tiredness)
Pain
Myalgia (muscle pain)
Rash
Urinary tract infection
White blood cell count increased
Pneumonia
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Lung infection

What are the common drug interactions of Ocrevus and Asa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abscess limb (limb infection)
Hyperglycaemia (high blood sugar)
Mouth ulceration (mouth ulcers)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Tendonitis (a condition that causes pain and swelling of tendons)
Tooth abscess (pus formation in tooth)
Urinary tract infection
Vaginal infection

40-49:

Gastroenteritis (inflammation of stomach and intestine)
Diarrhoea
Fatigue (feeling of tiredness)
Uhthoff's phenomenon (heat intolerance)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Migraine (headache)
Nervousness
Stress
Tooth infection

50-59:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Hemiparesis (weakness on one side of the body)
Lower respiratory tract infection
Lung infection
Malaise (a feeling of general discomfort or uneasiness)
Nervousness
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Asthenia (weakness)

60+:

Pain
Arthralgia (joint pain)
White blood cell count increased
Body temperature increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Hypotension (abnormally low blood pressure)
Influenza like illness
Infusion related reaction
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 13 people, 56.52%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 26.09%
Depression: 5 people, 21.74%
Pain: 2 people, 8.70%
Cough: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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