Ocrevus and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ocrevus (ocrelizumab) and Atarax (hydroxyzine hydrochloride). Common drug interactions include headache among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Ocrevus and Atarax. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

37 people who take Ocrevus and Atarax together, and have interactions are studied.

What are the common drug interactions of Ocrevus and Atarax, by gender? *:

female:

Headache (pain in head)
Oropharyngeal pain
Infusion related reaction
Fatigue (feeling of tiredness)
Drug ineffective
Gait disturbance
Pyrexia (fever)
Dizziness
Feeling hot
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Chest discomfort
Depression
Fatigue (feeling of tiredness)
Fungal infection
Immunosuppression
Infusion related reaction
Pain in extremity
Rash

What are the common drug interactions of Ocrevus and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Oropharyngeal pain
Throat irritation

30-39:

Fatigue (feeling of tiredness)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Back pain
Diarrhoea
Dyspepsia (indigestion)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Nausea (feeling of having an urge to vomit)
Polyp
Chest discomfort

40-49:

Serratia infection (bacterial infection)
Sputum discoloured
Weight increased
Asthenia (weakness)
Infusion related reaction
Oropharyngeal pain
Back pain
Headache (pain in head)
Gait disturbance
Dizziness

50-59:

Fatigue (feeling of tiredness)
Headache (pain in head)
Heart rate increased
Herpes zoster
Skin infection
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight increased
Chills (felling of cold)
Dry mouth
Dyspnoea (difficult or laboured respiration)

60+:

Cough
Heart rate increased
Lethargy (tiredness)
Oxygen saturation decreased
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory distress (difficulty in breathing)
Septic shock (shock due to blood infection)
Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
Urinary tract infection

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 20 people, 54.05%
Urinary Tract Infection: 6 people, 16.22%
Pain: 5 people, 13.51%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 10.81%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 10.81%
Hypoaesthesia (reduced sense of touch or sensation): 4 people, 10.81%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 10.81%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.11%
Seasonal Allergy (allergic condition due to certain season): 2 people, 5.41%
Progressive Multiple Sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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