Ocrevus and Glatiramer acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ocrevus (ocrelizumab) and Glatiramer acetate (glatiramer acetate). Common drug interactions include urinary tract infection among females and multiple sclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Ocrevus and Glatiramer acetate. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

What is Glatiramer acetate?

Glatiramer acetate has active ingredients of glatiramer acetate. eHealthMe is studying from 5,158 Glatiramer acetate users. Check the latest studies of Glatiramer acetate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

41 people who take Ocrevus and Glatiramer acetate together, and have interactions are studied.

Ocrevus and Glatiramer acetate drug interactions.

What are the common drug interactions of Ocrevus and Glatiramer Acetate, by gender? *:

female:

  1. Urinary tract infection
  2. Visual impairment
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Lung disorder (lung disease)
  5. Maternal exposure before pregnancy (use of substance before pregnancy)
  6. Headache (pain in head)
  7. Deafness
  8. Diarrhoea
  9. Discomfort
  10. Dysphagia (a condition in which swallowing is difficult or painful)

male:

  1. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Muscular weakness (muscle weakness)
  3. Arthropathy
  4. Walking disability
  5. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  6. Leukocytosis (increased white blood cells)
  7. Pneumonia
  8. Blood immunoglobulin g decreased
  9. Blood pressure increased
  10. Burning sensation

What are the common drug interactions of Ocrevus and Glatiramer Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Maternal exposure during pregnancy (use of substance during pregnancy)
  2. Premature baby
  3. Premature rupture of membranes
  4. Appendicitis (inflammation of the appendix)
  5. Malignant melanoma (skin cancer rises from melancytes)
  6. Metastases to central nervous system (cancer spreads to central nervous system)
  7. Nausea (feeling of having an urge to vomit)
  8. Neoplasm (tumour)

30-39:

  1. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Drug hypersensitivity
  3. Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

  1. Pneumonia
  2. Headache (pain in head)
  3. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Oropharyngeal pain
  5. Throat irritation

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Ear discomfort
  4. Headache (pain in head)
  5. Infection
  6. Weight increased
  7. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  8. Hepatic steatosis (fatty liver disease)
  9. Herpes zoster
  10. Human papilloma virus test positive

60+:

  1. Urinary tract infection
  2. Asthenia (weakness)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  5. Leukocytosis (increased white blood cells)
  6. Arthropathy
  7. Blood immunoglobulin g decreased
  8. Blood pressure increased
  9. Burning sensation
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 16 people, 39.02%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 12 people, 29.27%
  3. Muscle Spasms (muscle contraction): 4 people, 9.76%
  4. Urinary Tract Infection: 3 people, 7.32%
  5. Rickets (softening of bones): 3 people, 7.32%
  6. Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 7.32%
  7. Oral Herpes (viral infection of mouth): 3 people, 7.32%
  8. Depression: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ocrevus and Glatiramer acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ocrevus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glatiramer acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ocrevus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glatiramer acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ocrelizumab and glatiramer acetate (the active ingredients of Ocrevus and Glatiramer acetate, respectively), and Ocrevus and Glatiramer acetate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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