Ofev and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ofev (nintedanib esylate) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include dyspnoea among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Ofev and Bactrim ds. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

20 people who take Ofev and Bactrim ds together, and have interactions are studied.

What are the common drug interactions of Ofev and Bactrim Ds, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Cough
Diarrhoea
Fatigue (feeling of tiredness)
Pneumonia
Cardiac flutter (abnormal heart rhythm)
Dyspnoea exertional (breathlessness or shortness of breath)
Idiopathic pulmonary fibrosis (chronic lung disease)
Nausea (feeling of having an urge to vomit)
Sinusitis (inflammation of sinus)

male:

Nausea (feeling of having an urge to vomit)
Vomiting
Pruritus (severe itching of the skin)
Rash
Dyspnoea (difficult or laboured respiration)
Alopecia (absence of hair from areas of the body)
Diarrhoea
Oxygen saturation decreased
Prostate infection
Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the common drug interactions of Ofev and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Productive cough

60+:

Dyspnoea (difficult or laboured respiration)
Diarrhoea
Sinusitis (inflammation of sinus)
Hypotension (abnormally low blood pressure)
Abdominal discomfort
Chest discomfort
Ear disorder
Gastrointestinal pain
Hypoxia (low oxygen in tissues)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 10 people, 50.00%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 9 people, 45.00%
Multiple Myeloma (cancer of the plasma cells): 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.00%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.00%
Pain: 1 person, 5.00%
Osteoporosis (bones weak and more likely to break): 1 person, 5.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.00%
High Blood Pressure: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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