Ofev and Neoral drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ofev (nintedanib esylate) and Neoral (cyclosporine). Common drug interactions include mycobacterium abscessus infection among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Ofev and Neoral. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.
What is Ofev?
Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.
What is Neoral?
Neoral has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 26,084 Neoral users. Check the latest studies of Neoral.
27 people who take Ofev and Neoral together, and have interactions are studied.

What are the common drug interactions of Ofev and Neoral, by gender? *:
female:
- Mycobacterium abscessus infection (rapid growing bacterial infection)
- Platelet count decreased
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Renal impairment (severely reduced kidney function)
- Altered state of consciousness (altered state of mind)
- Constipation
- Hypertension (high blood pressure)
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Insomnia (sleeplessness)
- Interstitial lung disease
male:
- Pyrexia (fever)
- Hypotension (abnormally low blood pressure)
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Pneumonia
- Oral candidiasis (fungal infection of mouth)
- Hypertension (high blood pressure)
- Acne (skin problems that cause pimples)
- Bacterial infection
- Drug eruption (adverse drug reaction of the skin)
- Hepatic enzyme increased
What are the common drug interactions of Ofev and Neoral, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Acne (skin problems that cause pimples)
- Bacterial infection
- Diarrhoea
- Drug eruption (adverse drug reaction of the skin)
- Hepatic enzyme increased
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Infection
- Nasopharyngitis (inflammation of the nasopharynx)
- Oral candidiasis (fungal infection of mouth)
- Osteoporosis (bones weak and more likely to break)
50-59:
- Diarrhoea
- Herpes zoster
- Nausea (feeling of having an urge to vomit)
- Hypertension (high blood pressure)
60+:
- Hypotension (abnormally low blood pressure)
- Pyrexia (fever)
- Brain natriuretic peptide increased
- Hypertension (high blood pressure)
- Mycobacterium abscessus infection (rapid growing bacterial infection)
- Platelet count decreased
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Renal impairment (severely reduced kidney function)
- Altered state of consciousness (altered state of mind)
- Constipation
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 44.44%
- Idiopathic Pulmonary Fibrosis (chronic lung disease): 10 people, 37.04%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 33.33%
- Interstitial Lung Disease: 6 people, 22.22%
- Diabetes: 6 people, 22.22%
- Hyperkalemia (damage to or disease of the kidney): 4 people, 14.81%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 11.11%
- Pneumonia: 2 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Ofev and Neoral?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ofev and Neoral:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ofev:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neoral:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ofev and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neoral and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on nintedanib esylate and cyclosporine (the active ingredients of Ofev and Neoral, respectively), and Ofev and Neoral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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