Ofirmev and Metoclopramide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ofirmev (acetaminophen) and Metoclopramide (metoclopramide hydrochloride). Common drug interactions include pancreatitis acute among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Ofirmev and Metoclopramide. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Ofirmev?

Ofirmev has active ingredients of acetaminophen. eHealthMe is studying from 817 Ofirmev users. Check the latest studies of Ofirmev.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

On Jul, 17, 2026

23 people who take Ofirmev and Metoclopramide together, and have interactions are studied.

Ofirmev and Metoclopramide drug interactions.

What are the common drug interactions of Ofirmev and Metoclopramide, by gender? *:

female:

Pancreatitis acute (sudden inflammation of pancreas)
Burning sensation
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin lesion
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug ineffective
Dystonia (abnormal muscle tone)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Headache (pain in head)
Leukocytosis (increased white blood cells)
Post-traumatic neck syndrome
Psychomotor hyperactivity (feelings of extreme restlessness)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Ofirmev and Metoclopramide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Discomfort
Drug ineffective
Dystonia (abnormal muscle tone)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Headache (pain in head)
Leukocytosis (increased white blood cells)
Post-traumatic neck syndrome
Psychomotor hyperactivity (feelings of extreme restlessness)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

20-29:

Maternal exposure during pregnancy (use of substance during pregnancy)
Premature delivery

30-39:

Chest discomfort
Chest pain
Electrocardiogram t wave amplitude decreased
Electrocardiogram t wave inversion
Hypotension (abnormally low blood pressure)

40-49:

Burning sensation
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin lesion
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

50-59:

Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis (inflammation of pancreas)
Alanine aminotransferase increased
Aspartate aminotransferase increased

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Hypotension (abnormally low blood pressure)
Pain
Anaemia (lack of blood)
Embolic stroke (stroke due to obstruction due to an embolus)
Pulmonary embolism (blockage of the main artery of the lung)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Acidosis (build-up of carbon dioxide in the blood)
Arthralgia (joint pain)

What are the existing conditions these people have? *

Pain: 4 people, 17.39%
Nausea And Vomiting: 4 people, 17.39%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Skin Blushing/flushing (a sudden reddening of the face, neck): 2 people, 8.70%
Headache (pain in head): 2 people, 8.70%
Constipation: 2 people, 8.70%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 8.70%
Dehydration (dryness resulting from the removal of water): 2 people, 8.70%
Drug Eruption (adverse drug reaction of the skin): 2 people, 8.70%
Essential Hypertension (primary hypertension): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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