Ofloxacin and Neoral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ofloxacin (ofloxacin) and Neoral (cyclosporine). Common drug interactions include anaphylactic shock among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Ofloxacin and Neoral. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Ofloxacin?

Ofloxacin has active ingredients of ofloxacin. It is often used in urinary tract infection. eHealthMe is studying from 9,372 Ofloxacin users. Check the latest studies of Ofloxacin.

What is Neoral?

Neoral has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 26,084 Neoral users. Check the latest studies of Neoral.

On Aug, 07, 2026

21 people who take Ofloxacin and Neoral together, and have interactions are studied.

What are the common drug interactions of Ofloxacin and Neoral, by gender? *:

female:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Erythema (redness of the skin)
Feeling hot
Glossitis (infection of tongue with soreness)
Insomnia (sleeplessness)
Muscular weakness (muscle weakness)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)

male:

Blood creatinine increased
Blood urea increased
Confusional state
Cytomegalovirus infection
Diarrhoea
Encephalopathy (functioning of the brain is affected by some agent or condition)
Graft rejection (graft failure)
Hallucination, visual (seeing things that aren't there)
Multi-organ failure (multisystem organ failure)
Muscle rigidity (muscle stiffness)

What are the common drug interactions of Ofloxacin and Neoral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Dyspnoea (difficult or laboured respiration)
Generalised oedema (swelling all over the body)
Malaise (a feeling of general discomfort or uneasiness)
Oliguria (not enough urine)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

n/a

30-39:

Erythema (redness of the skin)
Feeling hot
Glossitis (infection of tongue with soreness)
Insomnia (sleeplessness)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash
Swollen tongue (swelling of tongue)
White blood cell count increased

40-49:

Blood creatinine increased
Blood urea increased
Epididymitis (pain in the scrotum or testicle)
Acidosis (build-up of carbon dioxide in the blood)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Muscle rigidity (muscle stiffness)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Renal failure (kidney dysfunction)
Tremor (trembling or shaking movements in one or more parts of your body)
Acute pulmonary oedema (sudden deposit of fluid in the lung))

50-59:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain
Blood creatinine increased
Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
Cytomegalovirus infection
Diarrhoea
Graft rejection (graft failure)
Hallucination, visual (seeing things that aren't there)
Anaemia (lack of blood)
Anaemia folate deficiency (lack of blood due to deficiency of folate)

60+:

Anaemia (lack of blood)
Arteriovenous fistula
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Confusional state
Multi-organ failure (multisystem organ failure)
Muscular weakness (muscle weakness)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Quadriparesis (muscle weakness affecting all four limbs)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 19.05%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 9.52%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 9.52%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 9.52%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 9.52%
Bacterial Sepsis: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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