Ogen and Humira drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ogen (estropipate) and Humira (adalimumab). Common drug interactions include depression among females.
The phase IV clinical study analyzes what interactions people have when they take Ogen and Humira. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Ogen?
Ogen has active ingredients of estropipate. eHealthMe is studying from 2,553 Ogen users. Check the latest studies of Ogen.
What is Humira?
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.
22 people who take Ogen and Humira together, and have interactions are studied.

What are the common drug interactions of Ogen and Humira, by gender? *:
female:
- Depression
- Hot flush (sudden feelings of heat)
- Oestrogen receptor assay positive
- Stress
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Deformity (disfigurement)
- Fatigue (feeling of tiredness)
- Hepatitis (inflammation of the liver)
- Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
- Injection site erythema (redness at injection site)
male:
n/a
What are the common drug interactions of Ogen and Humira, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anxiety disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Herpes zoster
- Mycotic allergy (fungal allergy)
- Respiratory disorder (respiratory disease)
- Hypertension (high blood pressure)
- Injection site pain
- Muscle spasms (muscle contraction)
30-39:
n/a
40-49:
- Arthralgia (joint pain)
- Fall
- Joint dislocation (a joint position is changed from normal position)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Eructation (release of gas from the digestive tract)
- Infection
- Melaena (the passage of black, tarry stools)
- Pain
50-59:
- Pneumonia
- Back disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cough
- Fall
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
- Hypersensitivity
- Injection site pain
- Loss of consciousness
60+:
- Depression
- Hot flush (sudden feelings of heat)
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Deformity (disfigurement)
- Hepatitis (inflammation of the liver)
- Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
- Injection site erythema (redness at injection site)
- Aortic valve stenosis (narrowing of the aortic valve)
- Asthenia (weakness)
- Carotid artery stenosis (narrowing of carotid artery)
What are the existing conditions these people have? *
- Pain: 5 people, 22.73%
- High Blood Cholesterol: 5 people, 22.73%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 18.18%
- Stress And Anxiety: 4 people, 18.18%
- Sleep Disorder: 3 people, 13.64%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 13.64%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
- High Blood Pressure: 2 people, 9.09%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
- Diabetes: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Ogen and Humira?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ogen and Humira:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Humira:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ogen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Humira and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on estropipate and adalimumab (the active ingredients of Ogen and Humira, respectively), and Ogen and Humira (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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